Letter to editor: Blood pressure, hypertension and lead exposure
Abstract A significant association of office diastolic blood pressure with low-level blood lead exposure was reported in a Brazilian adult population. However, caution should be taken to interpret these results. The multivariable-adjusted association with blood pressure was positive for diastolic bl...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-02-01
|
| Series: | Environmental Health |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12940-018-0364-3 |
| _version_ | 1819181724509143040 |
|---|---|
| author | Wen-Yi Yang Jan A. Staessen |
| author_facet | Wen-Yi Yang Jan A. Staessen |
| author_sort | Wen-Yi Yang |
| collection | DOAJ |
| description | Abstract A significant association of office diastolic blood pressure with low-level blood lead exposure was reported in a Brazilian adult population. However, caution should be taken to interpret these results. The multivariable-adjusted association with blood pressure was positive for diastolic blood pressure, but inverse for systolic blood pressure. The association sizes were infinitesimal without clinical relevance. The outcome measures, i.e. blood pressure and the prevalence of hypertension were analysed across categories of the blood lead distribution – not in relation to blood lead as continuous variable. Blood pressure was the average of two oscillometric office readings, whereas ambulatory monitoring is the state-of-the-art. |
| first_indexed | 2024-12-22T22:34:47Z |
| format | Article |
| id | doaj.art-3ec71c074312453881f9d0032bbf02d7 |
| institution | Directory Open Access Journal |
| issn | 1476-069X |
| language | English |
| last_indexed | 2024-12-22T22:34:47Z |
| publishDate | 2018-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Environmental Health |
| spelling | doaj.art-3ec71c074312453881f9d0032bbf02d72022-12-21T18:10:20ZengBMCEnvironmental Health1476-069X2018-02-011711410.1186/s12940-018-0364-3Letter to editor: Blood pressure, hypertension and lead exposureWen-Yi Yang0Jan A. Staessen1Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of LeuvenStudies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of LeuvenAbstract A significant association of office diastolic blood pressure with low-level blood lead exposure was reported in a Brazilian adult population. However, caution should be taken to interpret these results. The multivariable-adjusted association with blood pressure was positive for diastolic blood pressure, but inverse for systolic blood pressure. The association sizes were infinitesimal without clinical relevance. The outcome measures, i.e. blood pressure and the prevalence of hypertension were analysed across categories of the blood lead distribution – not in relation to blood lead as continuous variable. Blood pressure was the average of two oscillometric office readings, whereas ambulatory monitoring is the state-of-the-art.http://link.springer.com/article/10.1186/s12940-018-0364-3Ambulatory blood pressure monitoringBlood pressureEnvironmental medicineHypertensionLead |
| spellingShingle | Wen-Yi Yang Jan A. Staessen Letter to editor: Blood pressure, hypertension and lead exposure Environmental Health Ambulatory blood pressure monitoring Blood pressure Environmental medicine Hypertension Lead |
| title | Letter to editor: Blood pressure, hypertension and lead exposure |
| title_full | Letter to editor: Blood pressure, hypertension and lead exposure |
| title_fullStr | Letter to editor: Blood pressure, hypertension and lead exposure |
| title_full_unstemmed | Letter to editor: Blood pressure, hypertension and lead exposure |
| title_short | Letter to editor: Blood pressure, hypertension and lead exposure |
| title_sort | letter to editor blood pressure hypertension and lead exposure |
| topic | Ambulatory blood pressure monitoring Blood pressure Environmental medicine Hypertension Lead |
| url | http://link.springer.com/article/10.1186/s12940-018-0364-3 |
| work_keys_str_mv | AT wenyiyang lettertoeditorbloodpressurehypertensionandleadexposure AT janastaessen lettertoeditorbloodpressurehypertensionandleadexposure |