Poikiloderma vasculare atrophicans: A distinct clinical entity?
This paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the absence of Pautrier′s microabscess or atypical lymphoid cells. The biopsy specimen was positive for cluster of differentiation (CD) 8...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=2;spage=216;epage=216;aulast=Mahajan |
| _version_ | 1828886292891435008 |
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| author | Vikram K Mahajan Pushpinder S Chauhan Karaninder S Mehta Anju Lath Sharma |
| author_facet | Vikram K Mahajan Pushpinder S Chauhan Karaninder S Mehta Anju Lath Sharma |
| author_sort | Vikram K Mahajan |
| collection | DOAJ |
| description | This paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the absence of Pautrier′s microabscess or atypical lymphoid cells. The biopsy specimen was positive for cluster of differentiation (CD) 8 on immunohistochemical staining. Its exact pathogenesis remains obscure, and it remains unclear whether PVA actually is mycosis fungoides (MF), a forme fruste of MF, or a distinct and benign dermatosis with CD8+ phenotype that can perhaps be labeled as PVA. However, it has a long benign clinical course without progression to tumor stage of MF in most cases, and its status within the spectrum of cutaneous T-cell lymphoma remains poorly understood. Yet it is imperative to distinguish PVA from poikilodermic MF. |
| first_indexed | 2024-12-13T11:42:09Z |
| format | Article |
| id | doaj.art-3ec77cc6273c453f83e52c05cd0bd566 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-13T11:42:09Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-3ec77cc6273c453f83e52c05cd0bd5662022-12-21T23:47:36ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112015-01-0160221621610.4103/0019-5154.152566Poikiloderma vasculare atrophicans: A distinct clinical entity?Vikram K MahajanPushpinder S ChauhanKaraninder S MehtaAnju Lath SharmaThis paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the absence of Pautrier′s microabscess or atypical lymphoid cells. The biopsy specimen was positive for cluster of differentiation (CD) 8 on immunohistochemical staining. Its exact pathogenesis remains obscure, and it remains unclear whether PVA actually is mycosis fungoides (MF), a forme fruste of MF, or a distinct and benign dermatosis with CD8+ phenotype that can perhaps be labeled as PVA. However, it has a long benign clinical course without progression to tumor stage of MF in most cases, and its status within the spectrum of cutaneous T-cell lymphoma remains poorly understood. Yet it is imperative to distinguish PVA from poikilodermic MF.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=2;spage=216;epage=216;aulast=MahajanCollagen vascular disordersparapsoriasis poikilodermiquepoikilodermatous genodermatosespoikilodermic mycosis fungoides |
| spellingShingle | Vikram K Mahajan Pushpinder S Chauhan Karaninder S Mehta Anju Lath Sharma Poikiloderma vasculare atrophicans: A distinct clinical entity? Indian Journal of Dermatology Collagen vascular disorders parapsoriasis poikilodermique poikilodermatous genodermatoses poikilodermic mycosis fungoides |
| title | Poikiloderma vasculare atrophicans: A distinct clinical entity? |
| title_full | Poikiloderma vasculare atrophicans: A distinct clinical entity? |
| title_fullStr | Poikiloderma vasculare atrophicans: A distinct clinical entity? |
| title_full_unstemmed | Poikiloderma vasculare atrophicans: A distinct clinical entity? |
| title_short | Poikiloderma vasculare atrophicans: A distinct clinical entity? |
| title_sort | poikiloderma vasculare atrophicans a distinct clinical entity |
| topic | Collagen vascular disorders parapsoriasis poikilodermique poikilodermatous genodermatoses poikilodermic mycosis fungoides |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=2;spage=216;epage=216;aulast=Mahajan |
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