Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi
Background: Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for the treating physician. The symptoms of dengue may mimic other diseases such as leptospirosis, influenza A, Salmonella Typhi, Japanese encephalitis, chikungunya...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5270/9936_CE(Ra)_F(Sh)_PF1(NJAK)_PFA(Sh)_PF2(PAG).pdf |
| Summary: | Background: Concurrent infection with two agents can result
in an illness having overlapping symptoms creating a diagnostic
dilemma for the treating physician. The symptoms of dengue
may mimic other diseases such as leptospirosis, influenza A,
Salmonella Typhi, Japanese encephalitis, chikungunya and
malaria. There is paucity of data regarding dengue and typhoid
co- infection both in the developed and developing countries.
This study attempts to find the current co- infection rates in
North Delhi.
Materials and Methods: This retrospective study was done
between August and November 2013. Medical records of 659
patients exhibiting febrile illness who visited Kasturba Hospital
were studied. Dengue specific IgM antibodies were detected
by Dengue IgM antibody capture ELISA test. Serodiagnosis
of Salmonella infection was conducted by Widal test in the
hospital.
Results: Of the 659 febrile sera samples tested here, 141
(21.39%) tested positive for dengue. Of these 91 were females
and 50 males. Of the dengue cases, eleven were co-infected
with enteric fever (11/141= 7.8%). Maximum number of dengue
positive cases seen in age group 0-10 y. Case Fatality Rate
(CFR) was zero. Age groups of patients co-infected with dengue
and typhoid were as follows: 0-10 y: 5, 11-20 y: 3, 21-30 y: 2,
>60 y: 1.
Conclusion: Co-infection should always be kept in mind while
dealing with cases of dengue or enteric fever with or without
atypical features. In order to reduce the burden of disease, along
with improvement of sanitation and personal hygiene, emphasis
should be given on vaccination against typhoid. |
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| ISSN: | 2249-782X 0973-709X |