Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi
Background: Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for the treating physician. The symptoms of dengue may mimic other diseases such as leptospirosis, influenza A, Salmonella Typhi, Japanese encephalitis, chikungunya...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5270/9936_CE(Ra)_F(Sh)_PF1(NJAK)_PFA(Sh)_PF2(PAG).pdf |
| _version_ | 1811280587809357824 |
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| author | Yukti Sharma Vandana Arya Sanjay Jain Manoj Kumar Lopamudra Deka Anjali Mathur |
| author_facet | Yukti Sharma Vandana Arya Sanjay Jain Manoj Kumar Lopamudra Deka Anjali Mathur |
| author_sort | Yukti Sharma |
| collection | DOAJ |
| description | Background: Concurrent infection with two agents can result
in an illness having overlapping symptoms creating a diagnostic
dilemma for the treating physician. The symptoms of dengue
may mimic other diseases such as leptospirosis, influenza A,
Salmonella Typhi, Japanese encephalitis, chikungunya and
malaria. There is paucity of data regarding dengue and typhoid
co- infection both in the developed and developing countries.
This study attempts to find the current co- infection rates in
North Delhi.
Materials and Methods: This retrospective study was done
between August and November 2013. Medical records of 659
patients exhibiting febrile illness who visited Kasturba Hospital
were studied. Dengue specific IgM antibodies were detected
by Dengue IgM antibody capture ELISA test. Serodiagnosis
of Salmonella infection was conducted by Widal test in the
hospital.
Results: Of the 659 febrile sera samples tested here, 141
(21.39%) tested positive for dengue. Of these 91 were females
and 50 males. Of the dengue cases, eleven were co-infected
with enteric fever (11/141= 7.8%). Maximum number of dengue
positive cases seen in age group 0-10 y. Case Fatality Rate
(CFR) was zero. Age groups of patients co-infected with dengue
and typhoid were as follows: 0-10 y: 5, 11-20 y: 3, 21-30 y: 2,
>60 y: 1.
Conclusion: Co-infection should always be kept in mind while
dealing with cases of dengue or enteric fever with or without
atypical features. In order to reduce the burden of disease, along
with improvement of sanitation and personal hygiene, emphasis
should be given on vaccination against typhoid. |
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| format | Article |
| id | doaj.art-3ec7cfbbd0a4485db7c08dd2358f13c0 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-13T01:17:32Z |
| publishDate | 2014-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-3ec7cfbbd0a4485db7c08dd2358f13c02022-12-22T03:08:51ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-12-01812DC09DC1110.7860/JCDR/2014/9936.5270Dengue and Typhoid Co-infection– Study from a Government Hospital in North DelhiYukti Sharma0Vandana Arya1Sanjay Jain2Manoj Kumar3Lopamudra Deka4Anjali Mathur5Specialist, Department of Microbiology, Hindu Rao Hospital, Delhi, India.PHD, Department of Pathology, Kasturba Hospital, New Delhi, India.Head of Department, Department of Microbiology, Hindu Rao Hospital, Delhi, India.Senior Resident, Department of Microbiology, Hindu Rao Hospital, New Delhi, India.Specialist, Department of Pathology, Kasturba Hospital, Daryaganj, New Delhi, India.Chief Medical Officer, Department of Pathology/Microbiology, Kasturba Hospital, Daryaganj, New Delhi, India.Background: Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for the treating physician. The symptoms of dengue may mimic other diseases such as leptospirosis, influenza A, Salmonella Typhi, Japanese encephalitis, chikungunya and malaria. There is paucity of data regarding dengue and typhoid co- infection both in the developed and developing countries. This study attempts to find the current co- infection rates in North Delhi. Materials and Methods: This retrospective study was done between August and November 2013. Medical records of 659 patients exhibiting febrile illness who visited Kasturba Hospital were studied. Dengue specific IgM antibodies were detected by Dengue IgM antibody capture ELISA test. Serodiagnosis of Salmonella infection was conducted by Widal test in the hospital. Results: Of the 659 febrile sera samples tested here, 141 (21.39%) tested positive for dengue. Of these 91 were females and 50 males. Of the dengue cases, eleven were co-infected with enteric fever (11/141= 7.8%). Maximum number of dengue positive cases seen in age group 0-10 y. Case Fatality Rate (CFR) was zero. Age groups of patients co-infected with dengue and typhoid were as follows: 0-10 y: 5, 11-20 y: 3, 21-30 y: 2, >60 y: 1. Conclusion: Co-infection should always be kept in mind while dealing with cases of dengue or enteric fever with or without atypical features. In order to reduce the burden of disease, along with improvement of sanitation and personal hygiene, emphasis should be given on vaccination against typhoid.https://jcdr.net/articles/PDF/5270/9936_CE(Ra)_F(Sh)_PF1(NJAK)_PFA(Sh)_PF2(PAG).pdfdual infectionfebrile illnessnorth delhityphoid |
| spellingShingle | Yukti Sharma Vandana Arya Sanjay Jain Manoj Kumar Lopamudra Deka Anjali Mathur Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi Journal of Clinical and Diagnostic Research dual infection febrile illness north delhi typhoid |
| title | Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi |
| title_full | Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi |
| title_fullStr | Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi |
| title_full_unstemmed | Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi |
| title_short | Dengue and Typhoid Co-infection– Study from a Government Hospital in North Delhi |
| title_sort | dengue and typhoid co infection study from a government hospital in north delhi |
| topic | dual infection febrile illness north delhi typhoid |
| url | https://jcdr.net/articles/PDF/5270/9936_CE(Ra)_F(Sh)_PF1(NJAK)_PFA(Sh)_PF2(PAG).pdf |
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