Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties
Background:. Current approaches do not provide a practical method for the accurate prediction of a Cutibacterium periprosthetic joint infection (PJI) in failed arthroplasties. Thus, surgeons revising failed arthroplasties must decide whether to exchange the implants and to institute antibiotic treat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2020-12-01
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| Series: | JBJS Open Access |
| Online Access: | http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.20.00095 |
| _version_ | 1797375030820077568 |
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| author | Frederick A. Matsen, III, MD Anastasia Whitson, BSPH Jason E. Hsu, MD |
| author_facet | Frederick A. Matsen, III, MD Anastasia Whitson, BSPH Jason E. Hsu, MD |
| author_sort | Frederick A. Matsen, III, MD |
| collection | DOAJ |
| description | Background:. Current approaches do not provide a practical method for the accurate prediction of a Cutibacterium periprosthetic joint infection (PJI) in failed arthroplasties. Thus, surgeons revising failed arthroplasties must decide whether to exchange the implants and to institute antibiotic treatment without knowing the results of cultures of deep specimens obtained at the revision procedure. This study tests the hypothesis that the results of preoperative culture specimens of the skin surface obtained in the clinic can predict the presence of culture-positive Cutibacterium PJIs.
Methods:. Revision shoulder arthroplasties performed between October 3, 2017, and February 4, 2020, that had both preoperative clinic culture specimens and surgical culture specimens were included in this analysis. Culture results were assigned a value from 0 to 4. The percentage of the total skin bacterial load contributed by Cutibacterium (Cutibacterium percentage) was determined. To reduce concern about contamination, a robust criterion for culture-positive Cutibacterium PJI was applied: ≥2 surgical specimens with a Cutibacterium value of ≥1. The predictive values for a culture-positive Cutibacterium PJI were determined for a clinic skin culture Cutibacterium value of >1 and a clinic skin percentage of Cutibacterium of ≥75%.
Results:. Eighteen cases met the inclusion criteria; of these, 7 (6 male patients) met our criterion for a culture-positive Cutibacterium PJI. For all patients, a preoperative clinic skin Cutibacterium value of >1 predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 89%, and a clinic skin Cutibacterium percentage of ≥75% predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 94%. For male patients, a preoperative clinic skin Cutibacterium value of >1 predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 91%, and a clinic skin Cutibacterium percentage of ≥75% predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 100%.
Conclusions:. A simple culture specimen of the unprepared skin surface obtained in a clinic prior to revision shoulder arthroplasty may provide valuable assistance to surgeons planning a revision arthroplasty.
Level of Evidence:. Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence. |
| first_indexed | 2024-03-08T19:16:19Z |
| format | Article |
| id | doaj.art-3ecd0f03690046c3a28d1e782838b8ff |
| institution | Directory Open Access Journal |
| issn | 2472-7245 |
| language | English |
| last_indexed | 2024-03-08T19:16:19Z |
| publishDate | 2020-12-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | JBJS Open Access |
| spelling | doaj.art-3ecd0f03690046c3a28d1e782838b8ff2023-12-27T06:50:47ZengWolters KluwerJBJS Open Access2472-72452020-12-0154e20.00095e20.0009510.2106/JBJS.OA.20.00095JBJSOA2000095Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder ArthroplastiesFrederick A. Matsen, III, MD0Anastasia Whitson, BSPH1Jason E. Hsu, MD21 Department of Orthopedics and Sports Medicine, University of Washington, Seattle, Washington1 Department of Orthopedics and Sports Medicine, University of Washington, Seattle, Washington1 Department of Orthopedics and Sports Medicine, University of Washington, Seattle, WashingtonBackground:. Current approaches do not provide a practical method for the accurate prediction of a Cutibacterium periprosthetic joint infection (PJI) in failed arthroplasties. Thus, surgeons revising failed arthroplasties must decide whether to exchange the implants and to institute antibiotic treatment without knowing the results of cultures of deep specimens obtained at the revision procedure. This study tests the hypothesis that the results of preoperative culture specimens of the skin surface obtained in the clinic can predict the presence of culture-positive Cutibacterium PJIs. Methods:. Revision shoulder arthroplasties performed between October 3, 2017, and February 4, 2020, that had both preoperative clinic culture specimens and surgical culture specimens were included in this analysis. Culture results were assigned a value from 0 to 4. The percentage of the total skin bacterial load contributed by Cutibacterium (Cutibacterium percentage) was determined. To reduce concern about contamination, a robust criterion for culture-positive Cutibacterium PJI was applied: ≥2 surgical specimens with a Cutibacterium value of ≥1. The predictive values for a culture-positive Cutibacterium PJI were determined for a clinic skin culture Cutibacterium value of >1 and a clinic skin percentage of Cutibacterium of ≥75%. Results:. Eighteen cases met the inclusion criteria; of these, 7 (6 male patients) met our criterion for a culture-positive Cutibacterium PJI. For all patients, a preoperative clinic skin Cutibacterium value of >1 predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 89%, and a clinic skin Cutibacterium percentage of ≥75% predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 94%. For male patients, a preoperative clinic skin Cutibacterium value of >1 predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 91%, and a clinic skin Cutibacterium percentage of ≥75% predicted the presence of a culture-positive Cutibacterium PJI with an accuracy of 100%. Conclusions:. A simple culture specimen of the unprepared skin surface obtained in a clinic prior to revision shoulder arthroplasty may provide valuable assistance to surgeons planning a revision arthroplasty. Level of Evidence:. Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.20.00095 |
| spellingShingle | Frederick A. Matsen, III, MD Anastasia Whitson, BSPH Jason E. Hsu, MD Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties JBJS Open Access |
| title | Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties |
| title_full | Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties |
| title_fullStr | Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties |
| title_full_unstemmed | Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties |
| title_short | Preoperative Skin Cultures Predict Periprosthetic Infections in Revised Shoulder Arthroplasties |
| title_sort | preoperative skin cultures predict periprosthetic infections in revised shoulder arthroplasties |
| url | http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.20.00095 |
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