Residual Dipolar Couplings in Structure Determination of Natural Products
Abstract The determination of natural products stereochemistry remains a formidable task. Residual dipolar couplings (RDCs) induced by anisotropic media are a powerful tool for determination of the stereochemistry of organic molecule in solution. This review will provide a short introduction on RDCs...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-06-01
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| Series: | Natural Products and Bioprospecting |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1007/s13659-018-0174-x |
| _version_ | 1819071040521764864 |
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| author | Gao-Wei Li Han Liu Feng Qiu Xiao-Juan Wang Xin-Xiang Lei |
| author_facet | Gao-Wei Li Han Liu Feng Qiu Xiao-Juan Wang Xin-Xiang Lei |
| author_sort | Gao-Wei Li |
| collection | DOAJ |
| description | Abstract The determination of natural products stereochemistry remains a formidable task. Residual dipolar couplings (RDCs) induced by anisotropic media are a powerful tool for determination of the stereochemistry of organic molecule in solution. This review will provide a short introduction on RDCs-based methodology for the structural elucidation of natural products. Special attention is given to the current availability of alignment media in organic solvents. The applications of RDCs for structural analysis of some examples of natural products were discussed and summarized. Graphical Abstract This review provides a short introduction on RDCs-based methodology for the structural elucidation of natural products. Special attention is given to the current availability of alignment media in organic solvents. The applications of RDCs for structural analysis of some examples of natural products were discussed and summarized. |
| first_indexed | 2024-12-21T17:15:31Z |
| format | Article |
| id | doaj.art-3ecfeda6455948c69935ba82547256a7 |
| institution | Directory Open Access Journal |
| issn | 2192-2195 2192-2209 |
| language | English |
| last_indexed | 2024-12-21T17:15:31Z |
| publishDate | 2018-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Natural Products and Bioprospecting |
| spelling | doaj.art-3ecfeda6455948c69935ba82547256a72022-12-21T18:56:17ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092018-06-018427929510.1007/s13659-018-0174-xResidual Dipolar Couplings in Structure Determination of Natural ProductsGao-Wei Li0Han Liu1Feng Qiu2Xiao-Juan Wang3Xin-Xiang Lei4College of Chemistry and Chemical Engineering, Shangqiu Normal UniversitySchool of Pharmaceutical Sciences, South Central University for NationalitiesSchool of Pharmaceutical Sciences, South Central University for NationalitiesCollege of Chemistry and Chemical Engineering, Shangqiu Normal UniversitySchool of Pharmaceutical Sciences, South Central University for NationalitiesAbstract The determination of natural products stereochemistry remains a formidable task. Residual dipolar couplings (RDCs) induced by anisotropic media are a powerful tool for determination of the stereochemistry of organic molecule in solution. This review will provide a short introduction on RDCs-based methodology for the structural elucidation of natural products. Special attention is given to the current availability of alignment media in organic solvents. The applications of RDCs for structural analysis of some examples of natural products were discussed and summarized. Graphical Abstract This review provides a short introduction on RDCs-based methodology for the structural elucidation of natural products. Special attention is given to the current availability of alignment media in organic solvents. The applications of RDCs for structural analysis of some examples of natural products were discussed and summarized.http://link.springer.com/article/10.1007/s13659-018-0174-xNMR spectroscopyResidual dipolar couplingsAlignment mediaStructural elucidationNatural products |
| spellingShingle | Gao-Wei Li Han Liu Feng Qiu Xiao-Juan Wang Xin-Xiang Lei Residual Dipolar Couplings in Structure Determination of Natural Products Natural Products and Bioprospecting NMR spectroscopy Residual dipolar couplings Alignment media Structural elucidation Natural products |
| title | Residual Dipolar Couplings in Structure Determination of Natural Products |
| title_full | Residual Dipolar Couplings in Structure Determination of Natural Products |
| title_fullStr | Residual Dipolar Couplings in Structure Determination of Natural Products |
| title_full_unstemmed | Residual Dipolar Couplings in Structure Determination of Natural Products |
| title_short | Residual Dipolar Couplings in Structure Determination of Natural Products |
| title_sort | residual dipolar couplings in structure determination of natural products |
| topic | NMR spectroscopy Residual dipolar couplings Alignment media Structural elucidation Natural products |
| url | http://link.springer.com/article/10.1007/s13659-018-0174-x |
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