Effect of Lentivirus-induced shRNA Silencing CXCR4 Gene on Proliferation and Apoptosis in Human Esophageal Carcinoma Cell Line Eca109

Effect of Lentivirus-induced shRNA Silencing CXCR4 Gene on Proliferation and Apoptosis in Human Esophageal Carcinoma Cell Line Eca109

OBJECTIVE To discuss the application of the slow virus- induced short-hairpin RNA (vshRNA) to silence the expression of CXCR4 in EsCa cell lines Eca109, and observe the effect of silencing CXCR4 on the proliferation and apoptosis of Eca109 cells in vitro. METHODS The expression plasmid of vshR...

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Bibliographic Details
Main Authors: Dao-feng WANG, Ning LOU, Xiao-dong LI
Format: Article
Language:English
Published: China Anti-Cancer Association 2010-06-01
Series:Cancer Biology & Medicine
Subjects:
RNA
CXCR4
esophageal neoplasm
proliferation
apoptosis.
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/131

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