Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast

Abstract An extremely rare form of breast cancer, breast carcinosarcoma accounts for less than a percent of all breast malignancies and is highly aggressive. Composed of both cancerous epithelial and mesenchymal cell types, breast carcinosarcoma is associated with a poor prognosis compared to more c...

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Main Authors: Niels Vizgan, Tahereh Orouji Jokar, Ladan Enayati, Muhammad Salyana, Vladimir K. Gotlieb
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6020
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author Niels Vizgan
Tahereh Orouji Jokar
Ladan Enayati
Muhammad Salyana
Vladimir K. Gotlieb
author_facet Niels Vizgan
Tahereh Orouji Jokar
Ladan Enayati
Muhammad Salyana
Vladimir K. Gotlieb
author_sort Niels Vizgan
collection DOAJ
description Abstract An extremely rare form of breast cancer, breast carcinosarcoma accounts for less than a percent of all breast malignancies and is highly aggressive. Composed of both cancerous epithelial and mesenchymal cell types, breast carcinosarcoma is associated with a poor prognosis compared to more common breast cancers, and typically lack the receptors typical of other breast carcinomas, which minimize potential targets for treatment. In this case report, we discuss a 56‐year‐old patient affected by carcinosarcoma of the breast at a T2N1 stage, and the decision‐making process that factored into her treatment plan.
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spelling doaj.art-3ed1bbe71cc24308979807a18fec413d2022-12-22T03:40:38ZengWileyClinical Case Reports2050-09042022-07-01107n/an/a10.1002/ccr3.6020Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breastNiels Vizgan0Tahereh Orouji Jokar1Ladan Enayati2Muhammad Salyana3Vladimir K. Gotlieb4Department of Chemistry Wesleyan University Middletown Connecticut USASt. Mary's General Hospital Passaic New Jersey USADepartment of Haematology/Oncology Brookdale University Hospital and Medical Center Brooklyn New York USADepartment of Haematology/Oncology Brookdale University Hospital and Medical Center Brooklyn New York USADepartment of Haematology/Oncology Brookdale University Hospital and Medical Center Brooklyn New York USAAbstract An extremely rare form of breast cancer, breast carcinosarcoma accounts for less than a percent of all breast malignancies and is highly aggressive. Composed of both cancerous epithelial and mesenchymal cell types, breast carcinosarcoma is associated with a poor prognosis compared to more common breast cancers, and typically lack the receptors typical of other breast carcinomas, which minimize potential targets for treatment. In this case report, we discuss a 56‐year‐old patient affected by carcinosarcoma of the breast at a T2N1 stage, and the decision‐making process that factored into her treatment plan.https://doi.org/10.1002/ccr3.6020hematologymetaplastic breast canceroncologytriple‐negative breast cancer
spellingShingle Niels Vizgan
Tahereh Orouji Jokar
Ladan Enayati
Muhammad Salyana
Vladimir K. Gotlieb
Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
Clinical Case Reports
hematology
metaplastic breast cancer
oncology
triple‐negative breast cancer
title Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
title_full Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
title_fullStr Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
title_full_unstemmed Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
title_short Presentation and treatment of aggressive, Triple‐Negative carcinosarcoma of the breast
title_sort presentation and treatment of aggressive triple negative carcinosarcoma of the breast
topic hematology
metaplastic breast cancer
oncology
triple‐negative breast cancer
url https://doi.org/10.1002/ccr3.6020
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