Combinatorial Chemistry

In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products. Was the correct product produced? Were all th...

Full description

Bibliographic Details
Main Author: Renato Zenobi
Format: Article
Language:deu
Published: Swiss Chemical Society 2000-01-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/3211
_version_ 1818294992607641600
author Renato Zenobi
author_facet Renato Zenobi
author_sort Renato Zenobi
collection DOAJ
description In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products. Was the correct product produced? Were all the possible products produced? What is their purity? Where in a combinatorial library are the 'hits'? If a relatively large number of lead compounds or hits have been identified, what is the most effective way for their thorough chemical analysis? The key goals of this symposium were to provide an overview over the current state-of-the-art analytical strategies used in combinatorial chemistry, and to show how obstacles can be overcome by new analytical tools and strategies. It was fascinating to experience how many areas of chemistry are influenced by combinatorial chemistry nowadays, and it was impressive to witness the efforts being made by software developers and chemists alike to overcome some remaining hurdles in this area.
first_indexed 2024-12-13T03:40:34Z
format Article
id doaj.art-3ed22185bd8d4e92897362e549786e3f
institution Directory Open Access Journal
issn 0009-4293
2673-2424
language deu
last_indexed 2024-12-13T03:40:34Z
publishDate 2000-01-01
publisher Swiss Chemical Society
record_format Article
series CHIMIA
spelling doaj.art-3ed22185bd8d4e92897362e549786e3f2022-12-22T00:00:58ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242000-01-01541-2Combinatorial ChemistryRenato Zenobi In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products. Was the correct product produced? Were all the possible products produced? What is their purity? Where in a combinatorial library are the 'hits'? If a relatively large number of lead compounds or hits have been identified, what is the most effective way for their thorough chemical analysis? The key goals of this symposium were to provide an overview over the current state-of-the-art analytical strategies used in combinatorial chemistry, and to show how obstacles can be overcome by new analytical tools and strategies. It was fascinating to experience how many areas of chemistry are influenced by combinatorial chemistry nowadays, and it was impressive to witness the efforts being made by software developers and chemists alike to overcome some remaining hurdles in this area. https://www.chimia.ch/chimia/article/view/3211Analytical chemistryCombinatorial chemistryIlmac
spellingShingle Renato Zenobi
Combinatorial Chemistry
CHIMIA
Analytical chemistry
Combinatorial chemistry
Ilmac
title Combinatorial Chemistry
title_full Combinatorial Chemistry
title_fullStr Combinatorial Chemistry
title_full_unstemmed Combinatorial Chemistry
title_short Combinatorial Chemistry
title_sort combinatorial chemistry
topic Analytical chemistry
Combinatorial chemistry
Ilmac
url https://www.chimia.ch/chimia/article/view/3211
work_keys_str_mv AT renatozenobi combinatorialchemistry