Is an opioid-free anaesthesia possible without using alpha-2 agonists?

Opioid-free anaesthesia (OFA) is an anaesthetic technique where non-opioid drugs are used in the intraoperative period. It can be successful without using alpha-2 agonists, which are main drugs used in this multimodal anaesthesia. We are presenting seven different cases where OFA was used in differe...

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Main Authors: Marija Toleska, Aleksandar Dimitrovski
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Anaesthesia
Subjects:
Online Access:http://www.ijaweb.org/article.asp?issn=0019-5049;year=2020;volume=64;issue=5;spage=428;epage=431;aulast=Toleska
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author Marija Toleska
Aleksandar Dimitrovski
author_facet Marija Toleska
Aleksandar Dimitrovski
author_sort Marija Toleska
collection DOAJ
description Opioid-free anaesthesia (OFA) is an anaesthetic technique where non-opioid drugs are used in the intraoperative period. It can be successful without using alpha-2 agonists, which are main drugs used in this multimodal anaesthesia. We are presenting seven different cases where OFA was used in different abdominal surgeries (laparoscopic cholecystectomy, colon cancer operation, and laparoscopic inguinal hernia repair) alone or in a combination with epidural anaesthesia and peripheral nerve block. Prior induction to general anaesthesia all patients received dexamethasone and paracetamol. Induction of general anaesthesia consisted of giving midazolam, lignocaine, propofol, ketamine, and rocuronium. After tracheal intubation anaesthesia was maintained with sevoflurane and continuous infusion with lignocaine, magnesium sulphate, and ketamine (in some patients). At the end of the surgery, all patients received metamizole. The postoperative pain scores were reduced in most of the patients without giving opioids.
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spelling doaj.art-3ed6566c00e64d49a785210470b76c262022-12-21T19:52:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50490976-28172020-01-0164542843110.4103/ija.IJA_664_19Is an opioid-free anaesthesia possible without using alpha-2 agonists?Marija ToleskaAleksandar DimitrovskiOpioid-free anaesthesia (OFA) is an anaesthetic technique where non-opioid drugs are used in the intraoperative period. It can be successful without using alpha-2 agonists, which are main drugs used in this multimodal anaesthesia. We are presenting seven different cases where OFA was used in different abdominal surgeries (laparoscopic cholecystectomy, colon cancer operation, and laparoscopic inguinal hernia repair) alone or in a combination with epidural anaesthesia and peripheral nerve block. Prior induction to general anaesthesia all patients received dexamethasone and paracetamol. Induction of general anaesthesia consisted of giving midazolam, lignocaine, propofol, ketamine, and rocuronium. After tracheal intubation anaesthesia was maintained with sevoflurane and continuous infusion with lignocaine, magnesium sulphate, and ketamine (in some patients). At the end of the surgery, all patients received metamizole. The postoperative pain scores were reduced in most of the patients without giving opioids.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2020;volume=64;issue=5;spage=428;epage=431;aulast=Toleskaabdominal surgeryanalgesiaopioid free anaesthesiapostoperative pain
spellingShingle Marija Toleska
Aleksandar Dimitrovski
Is an opioid-free anaesthesia possible without using alpha-2 agonists?
Indian Journal of Anaesthesia
abdominal surgery
analgesia
opioid free anaesthesia
postoperative pain
title Is an opioid-free anaesthesia possible without using alpha-2 agonists?
title_full Is an opioid-free anaesthesia possible without using alpha-2 agonists?
title_fullStr Is an opioid-free anaesthesia possible without using alpha-2 agonists?
title_full_unstemmed Is an opioid-free anaesthesia possible without using alpha-2 agonists?
title_short Is an opioid-free anaesthesia possible without using alpha-2 agonists?
title_sort is an opioid free anaesthesia possible without using alpha 2 agonists
topic abdominal surgery
analgesia
opioid free anaesthesia
postoperative pain
url http://www.ijaweb.org/article.asp?issn=0019-5049;year=2020;volume=64;issue=5;spage=428;epage=431;aulast=Toleska
work_keys_str_mv AT marijatoleska isanopioidfreeanaesthesiapossiblewithoutusingalpha2agonists
AT aleksandardimitrovski isanopioidfreeanaesthesiapossiblewithoutusingalpha2agonists