Molecular Mechanism of Lipotoxicity as an Interesting Aspect in the Development of Pathological States—Current View of Knowledge

Molecular Mechanism of Lipotoxicity as an Interesting Aspect in the Development of Pathological States—Current View of Knowledge

Free fatty acids (FFAs) play numerous vital roles in the organism, such as contribution to energy generation and reserve, serving as an essential component of the cell membrane, or as ligands for nuclear receptors. However, the disturbance in fatty acid homeostasis, such as inefficient metabolism or...

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Bibliographic Details
Main Authors: Katarzyna Lipke, Adriana Kubis-Kubiak, Agnieszka Piwowar
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
lipotoxicity
fatty acid
oxidative stress
insulin resistance
inflammation
Online Access:https://www.mdpi.com/2073-4409/11/5/844

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