Pleiotropic Role of Puupehenones in Biomedical Research

Pleiotropic Role of Puupehenones in Biomedical Research

Marine sponges represent a vast source of metabolites with very interesting potential biomedical applications. Puupehenones are sesquiterpene quinones isolated from sponges of the orders Verongida and Dictyoceratida. This family of chemical compounds is composed of a high number of metabolites, incl...

Full description

Bibliographic Details
Main Authors:	Beatriz Martínez-Poveda, Ana R. Quesada, Miguel Ángel Medina
Format:	Article
Language:	English
Published:	MDPI AG 2017-10-01
Series:	Marine Drugs
Subjects:	puupehenones sponges marine drugs antiangiogenic antitumoral
Online Access:	https://www.mdpi.com/1660-3397/15/10/325

Similar Items

Marine Puupehenone and Puupehedione: Synthesis and Future Perspectives
by: Antonio Rosales Martínez, et al.
Published: (2023-05-01)

Danthron, an Anthraquinone Isolated from a Marine Fungus, Is a New Inhibitor of Angiogenesis Exhibiting Interesting Antitumor and Antioxidant Properties
by: Isabel Vidal, et al.
Published: (2023-05-01)

Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug
by: Javier A. García-Vilas, et al.
Published: (2015-12-01)

Effect of the Marine Polyketide Plocabulin on Tumor Progression
by: Eleonora Turrini, et al.
Published: (2022-12-01)

Editorial: Are natural products, used as antitumoral/antiangiogenic agents, less toxic than synthetic conventional chemotherapy?
by: Cecilia Veronica Nunez, et al.
Published: (2022-10-01)

Photodynamic therapy – hypericin tetraether liposome conjugates and their antitumor and antiangiogenic activity
by: Nikola Plenagl, et al.
Published: (2019-01-01)

Natural Products Derived from Marine Sponges with Antitumor Potential against Lung Cancer: A Systematic Review
by: Alba Ortigosa-Palomo, et al.
Published: (2024-02-01)

A Lactose-Binding Lectin from the Marine Sponge Cinachyrella Apion (Cal) Induces Cell Death in Human Cervical Adenocarcinoma Cells
by: Adriana Uchoa, et al.
Published: (2012-03-01)

Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
by: Eleonora Turrini, et al.
Published: (2023-05-01)

Exploring the Antiangiogenic Potential of Solomonamide A Bioactive Precursors: In Vitro and In Vivo Evidences of the Inhibitory Activity of Solo F-OH During Angiogenesis
by: Paloma Carrillo, et al.
Published: (2019-04-01)

Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol
by: Iván Cheng-Sánchez, et al.
Published: (2019-08-01)

Microarray-Based Transcriptional Profiling of Renieramycin M and Jorunnamycin C, Isolated from Thai Marine Organisms
by: Takatoshi Kawai, et al.
Published: (2009-10-01)

Clinical and laboratory signs and risk factors for nephrotoxicity, associated with antiangiogenic drugs
by: Katerina S. Grechukhina, et al.
Published: (2021-06-01)

Progress on angiogenic and antiangiogenic agents in the tumor microenvironment
by: Jian Xu, et al.
Published: (2024-11-01)

Terpenes extracted from marine sponges with antioxidant activity: a systematic review
by: Cintia Cristina Santi Martignago, et al.
Published: (2023-08-01)

Nephrotoxicity of anti-angiogenesis drugs
by: Katerina S. Grechukhina, et al.
Published: (2020-07-01)

Screening of antiangiogenic potential of twenty two marine invertebrate extracts of phylum Mollusca from South East Coast of India
by: Pankaj Gupta, et al.
Published: (2014-05-01)

Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives
by: Mohammad Ferdous Mehbub, et al.
Published: (2014-08-01)

Osteonecrosis of the Jaw during Lenvatinib Therapy: A Case Report Based on Surgical Management
by: Gen Udagawa, et al.
Published: (2019-11-01)

Non-coding RNA-related antitumor mechanisms of marine-derived agents
by: Zhixia Zhou, et al.
Published: (2022-12-01)

Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities
by: Maiy Y. Jaballah, et al.
Published: (2019-01-01)

Cytotoxic Alkaloids Derived from Marine Sponges: A Comprehensive Review
by: Ahmed M. Elissawy, et al.
Published: (2021-02-01)

Bioactivity Screening of Antarctic Sponges Reveals Anticancer Activity and Potential Cell Death via Ferroptosis by Mycalols
by: Gennaro Riccio, et al.
Published: (2021-08-01)

Marine Drugs from Sponge-Microbe Association—A Review
by: Tresa Remya A. Thomas, et al.
Published: (2010-04-01)

Medication-Related Osteonecrosis of the Jaw in Patients Treated Concurrently with Antiresorptive and Antiangiogenic Agents: Systematic Review and Meta-Analysis
by: Akanksha Srivastava, et al.
Published: (2021-11-01)

Antinociceptive and Anti-inflammatory Activities of Marine Sponges Aplysina Caissara, Haliclona sp. and Dragmacidon Reticulatum
by: Mariana Appel Hort, et al.
Published: (2018-11-01)

Marine-Derived Polymers in Ionic Liquids: Architectures Development and Biomedical Applications
by: Simone S. Silva, et al.
Published: (2020-06-01)

Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp. petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei Isolantion and biological activities of secondary metabolites from the sponges monanchora aff. arbuscula, aplysina sp. petromica ciocalyptoides and topsentia ophiraphidies, from the ascidian didemnum ligulum and from the octocoral carijoa riisei
by: Miriam H. Kossuga, et al.
Published: (2007-10-01)

Callyspongia crassa and C. siphonella (Porifera, Callyspongiidae) as a potential source for medical bioactive substances, Aqaba Gulf, Red Sea, Egypt
by: Hassan A. H. Ibrahim, et al.
Published: (2017-12-01)

Promising Antiparasitic Natural and Synthetic Products from Marine Invertebrates and Microorganisms
by: Mingyue Zhang, et al.
Published: (2023-01-01)

Bioactive Sesterterpenes and Triterpenes from Marine Sponges: Occurrence and Pharmacological Significance
by: WenHan Lin, et al.
Published: (2010-02-01)

Relative and Absolute Stereochemistry of Diacarperoxides: Antimalarial Norditerpene Endoperoxides from Marine Sponge Diacarnus megaspinorhabdosa
by: Fan Yang, et al.
Published: (2014-08-01)

Alcalóides alquilpiridínicos de esponjas marinhas Alkylpyridine alkaloids from marine sponges
by: Adaíla M. P. Almeida, et al.
Published: (1997-04-01)

Glycerolipids from a Sarcotragus Species Sponge
by: Si Zhang, et al.
Published: (2006-09-01)

INHIBITORY ACTIVITY OF SOME MARINE SPONGE EXTRACTS FROM URABÁ GULF ON DIHYDROFOLATE REDUCTASE ENZYME
by: Diego A. ZABALA, et al.
Published: (2009-02-01)

Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic Insights
by: Salman Ahmed, et al.
Published: (2022-07-01)

Aaptamine: A Versatile Marine Alkaloid for Antioxidant, Antibacterial, and Anticancer Therapeutics
by: Navin Kumar Tailor, et al.
Published: (2024-08-01)

Marine-Sourced Anti-Cancer and Cancer Pain Control Agents in Clinical and Late Preclinical Development
by: David J. Newman, et al.
Published: (2014-01-01)

The Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NF-κB Pathway
by: Isabel Vidal, et al.
Published: (2022-09-01)

MODERN IDEAS ABOUT THE COMBINATION OF RADIATION THERAPY WITH ANTIANGIOGENIC DRUGS IN THE TREATMENT OF PATIENTS WITH BRAIN METASTASES
by: O. I. Kit, et al.
Published: (2020-03-01)