Ontogeny of intestinal epithelial innate immune responses
Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus impact on disea...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-10-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00474/full |
| _version_ | 1811227828282195968 |
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| author | Mathias W. Hornef Mathias W. Hornef Marcus eFulde |
| author_facet | Mathias W. Hornef Mathias W. Hornef Marcus eFulde |
| author_sort | Mathias W. Hornef |
| collection | DOAJ |
| description | Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus impact on diseases susceptibility and health during adult life. The present review aims at summarizing the current understanding of the intestinal epithelial innate immune system and its developmental and adaptive changes after birth. |
| first_indexed | 2024-04-12T09:48:30Z |
| format | Article |
| id | doaj.art-3edb8a0dd3f34c29a08ebd2626d3c645 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-12T09:48:30Z |
| publishDate | 2014-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-3edb8a0dd3f34c29a08ebd2626d3c6452022-12-22T03:37:53ZengFrontiers Media S.A.Frontiers in Immunology1664-32242014-10-01510.3389/fimmu.2014.00474109268Ontogeny of intestinal epithelial innate immune responsesMathias W. Hornef0Mathias W. Hornef1Marcus eFulde2Hannover Medical SchoolRWTH UniversityHannover Medical SchoolEmerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus impact on diseases susceptibility and health during adult life. The present review aims at summarizing the current understanding of the intestinal epithelial innate immune system and its developmental and adaptive changes after birth.http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00474/fullInfectionInflammationAntimicrobial peptidedevelopmentinnate immunitymucosal immunology |
| spellingShingle | Mathias W. Hornef Mathias W. Hornef Marcus eFulde Ontogeny of intestinal epithelial innate immune responses Frontiers in Immunology Infection Inflammation Antimicrobial peptide development innate immunity mucosal immunology |
| title | Ontogeny of intestinal epithelial innate immune responses |
| title_full | Ontogeny of intestinal epithelial innate immune responses |
| title_fullStr | Ontogeny of intestinal epithelial innate immune responses |
| title_full_unstemmed | Ontogeny of intestinal epithelial innate immune responses |
| title_short | Ontogeny of intestinal epithelial innate immune responses |
| title_sort | ontogeny of intestinal epithelial innate immune responses |
| topic | Infection Inflammation Antimicrobial peptide development innate immunity mucosal immunology |
| url | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00474/full |
| work_keys_str_mv | AT mathiaswhornef ontogenyofintestinalepithelialinnateimmuneresponses AT mathiaswhornef ontogenyofintestinalepithelialinnateimmuneresponses AT marcusefulde ontogenyofintestinalepithelialinnateimmuneresponses |