Aminoglycosides-Related Ototoxicity: Mechanisms, Risk Factors, and Prevention in Pediatric Patients

Aminoglycosides-Related Ototoxicity: Mechanisms, Risk Factors, and Prevention in Pediatric Patients

Aminoglycosides are broad-spectrum antibiotics largely used in children, but they have potential toxic side effects, including ototoxicity. Ototoxicity from aminoglycosides is permanent and is a consequence of its action on the inner ear cells via multiple mechanisms. Both uncontrollable risk factor...

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Bibliographic Details
Main Authors: Serena Rivetti, Alberto Romano, Stefano Mastrangelo, Giorgio Attinà, Palma Maurizi, Antonio Ruggiero
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
aminoglycosides
children
ototoxicity
antibiotics
antibiotic side effects
childhood
Online Access:https://www.mdpi.com/1424-8247/16/10/1353

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