<b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738

Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenot...

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Main Authors: Tácito Pessoa Souza Junior, Ricardo Yukio Asano, Jonato Prestes, Marcelo Magalhães Sales, João Maurício Coelho, Herbert Gustavo Simões
Format: Article
Language:English
Published: Universidade Estadual de Maringá 2012-09-01
Series:Revista da Educação Física
Subjects:
Online Access:http://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738
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author Tácito Pessoa Souza Junior
Ricardo Yukio Asano
Jonato Prestes
Marcelo Magalhães Sales
João Maurício Coelho
Herbert Gustavo Simões
author_facet Tácito Pessoa Souza Junior
Ricardo Yukio Asano
Jonato Prestes
Marcelo Magalhães Sales
João Maurício Coelho
Herbert Gustavo Simões
author_sort Tácito Pessoa Souza Junior
collection DOAJ
description Nitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.
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spelling doaj.art-3ee0e22ac8cc4eb3a9c8c034595081be2022-12-22T02:40:17ZengUniversidade Estadual de MaringáRevista da Educação Física0103-39481983-30832012-09-012334694818847<b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738Tácito Pessoa Souza JuniorRicardo Yukio AsanoJonato PrestesMarcelo Magalhães SalesJoão Maurício CoelhoHerbert Gustavo SimõesNitric oxide (NO) is a potent vasodilator and hence has a major role in controlling vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension and others. Moreover, genotype and/or phenotype may reduce the bioavailability of NO resulting in severe endothelial dysfunction, increased peripheral vascular resistance. Recent research has shown that exercise increases the bioavailability of NO in acute and chronic forms. But the production of knowledge related to NO-mediated exercise still has gaps. Thus, the purpose of this brief review is to try elucidate the cellular mechanisms involved in the synthesis and regulation of NO, and demonstrate the advancement of scientific knowledge related to the bioavailability of NO mediated by exercise. For this review were used books and periodicals from the PubMed, HIGWIRE, SciELO and LILACS used “nitric oxide” and “exercise” to search. The main considerations in the study were that exercise increase the acute bioavailability of NO and chronic adaptations of exercise in relation to cardiovascular parameters are dependent on the increased bioavailability of NO induced by exercise.http://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738Óxido nítricoExercício.
spellingShingle Tácito Pessoa Souza Junior
Ricardo Yukio Asano
Jonato Prestes
Marcelo Magalhães Sales
João Maurício Coelho
Herbert Gustavo Simões
<b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
Revista da Educação Física
Óxido nítrico
Exercício.
title <b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
title_full <b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
title_fullStr <b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
title_full_unstemmed <b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
title_short <b>Nitric oxide and exercise: a review</b> - doi: 10.4025/reveducfis.v23i3.11738
title_sort b nitric oxide and exercise a review b doi 10 4025 reveducfis v23i3 11738
topic Óxido nítrico
Exercício.
url http://periodicos.uem.br/ojs/index.php/RevEducFis/article/view/11738
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