Rapid sensitive validated UPLCâMS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study
A new ultra-performance liquid chromatographyâelectrospray ionization mass spectrometry (UPLCâMS/ESI) method for simultaneous determination of venlafaxine (VEN) and its metabolite O-desmethylvenlafaxine (ODV) in rat plasma has been developed and validated using Venlafaxine d6 as the internal standar...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-12-01
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Series: | Journal of Pharmaceutical Analysis |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177913000567 |