Rapid sensitive validated UPLCâMS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study

Rapid sensitive validated UPLCâMS method for determination of venlafaxine and its metabolite in rat plasma: Application to pharmacokinetic study

A new ultra-performance liquid chromatographyâelectrospray ionization mass spectrometry (UPLCâMS/ESI) method for simultaneous determination of venlafaxine (VEN) and its metabolite O-desmethylvenlafaxine (ODV) in rat plasma has been developed and validated using Venlafaxine d6 as the internal standar...

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Bibliographic Details
Main Authors:	Sunil Kumar Dubey, R.N. Saha, Hemanth Jangala, S. Pasha
Format:	Article
Language:	English
Published:	Elsevier 2013-12-01
Series:	Journal of Pharmaceutical Analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177913000567

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