Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement
Background : This study aimed to compare preliminary data on the outcomes of sutureless aortic valve replacement (SU-AVR) with those of aortic valve replacement (AVR). Methods : We conducted a retrospective study of SU-AVR in moderate- to high-risk patients from 2013 to 2016. Matching was performed...
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| Format: | Article |
| Language: | English |
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Korean Society for Thoracic and Cardiovascular Surgery
2018-06-01
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| Series: | Korean Journal of Thoracic and Cardiovascular Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.5090/kjtcs.2018.51.3.172 |
| _version_ | 1818684797999906816 |
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| author | Puwadon Thitivaraporn Sarun Chiramongkol Dittapol Muntham Nopporn Pornpatrtanarak Chanapong Kittayarak Jule Namchaisiri Seri Singhatanadgige Pat Ongcharit Vichai Benjacholamas |
| author_facet | Puwadon Thitivaraporn Sarun Chiramongkol Dittapol Muntham Nopporn Pornpatrtanarak Chanapong Kittayarak Jule Namchaisiri Seri Singhatanadgige Pat Ongcharit Vichai Benjacholamas |
| author_sort | Puwadon Thitivaraporn |
| collection | DOAJ |
| description | Background : This study aimed to compare preliminary data on the outcomes of sutureless aortic valve replacement (SU-AVR) with those of aortic valve replacement (AVR). Methods : We conducted a retrospective study of SU-AVR in moderate- to high-risk patients from 2013 to 2016. Matching was performed at a 1:1 ratio using the Society of Thoracic Surgeons predicted risk of mortality score with sex and age. The primary outcome was 30-day mortality. The secondary outcomes were operative outcomes and complications. Results : A total of 277 patients were studied. Ten patients (50% males; median age, 81.5 years) underwent SU-AVR. Postoperative echocardiography showed impressive outcomes in the SU-AVR group. The 30-day mortality was 10% in both groups. In our study, the patients in the SU-AVR group developed postoperative thrombocytopenia. Platelet counts decreased from 225X103 /μL preoperatively to 94.5, 54.5, and 50.1X10 3/μL on postoperative days 1, 2, and 3, respectively, showing significant differences compared with the AVR group (p=0.04, p=0.16, and p=0.20, respectively). The median amount of platelet transfusion was higher in the AVR group (12.5 vs. 0 units, p=0.052). Conclusion : There was no difference in the 30-day mortality of moderate- to high-risk patients depending on whether they underwent SU-AVR or AVR. Although SU-AVR is associated with favorable cardiopulmonary bypass and cross-clamp times, it may be associated with postoperative thrombocytopenia. |
| first_indexed | 2024-12-17T10:56:21Z |
| format | Article |
| id | doaj.art-3ee41699f5cb4b1fa0b1e7f59ce1bf0b |
| institution | Directory Open Access Journal |
| issn | 2233-601X |
| language | English |
| last_indexed | 2024-12-17T10:56:21Z |
| publishDate | 2018-06-01 |
| publisher | Korean Society for Thoracic and Cardiovascular Surgery |
| record_format | Article |
| series | Korean Journal of Thoracic and Cardiovascular Surgery |
| spelling | doaj.art-3ee41699f5cb4b1fa0b1e7f59ce1bf0b2022-12-21T21:51:47ZengKorean Society for Thoracic and Cardiovascular SurgeryKorean Journal of Thoracic and Cardiovascular Surgery2233-601X2018-06-0151317217910.5090/kjtcs.2018.51.3.172kjtcs.2018.51.3.172Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve ReplacementPuwadon Thitivaraporn0Sarun Chiramongkol1Dittapol Muntham2Nopporn Pornpatrtanarak3Chanapong Kittayarak4Jule Namchaisiri5Seri Singhatanadgige6Pat Ongcharit7Vichai Benjacholamas8Cardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalSection of Mathematic, Faculty of Science and Technology, Rajamangala University of Technology SuvarnabhumiCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalCardiovascular and Thoracic Surgery Unit, King Chulalongkorn Memorial HospitalBackground : This study aimed to compare preliminary data on the outcomes of sutureless aortic valve replacement (SU-AVR) with those of aortic valve replacement (AVR). Methods : We conducted a retrospective study of SU-AVR in moderate- to high-risk patients from 2013 to 2016. Matching was performed at a 1:1 ratio using the Society of Thoracic Surgeons predicted risk of mortality score with sex and age. The primary outcome was 30-day mortality. The secondary outcomes were operative outcomes and complications. Results : A total of 277 patients were studied. Ten patients (50% males; median age, 81.5 years) underwent SU-AVR. Postoperative echocardiography showed impressive outcomes in the SU-AVR group. The 30-day mortality was 10% in both groups. In our study, the patients in the SU-AVR group developed postoperative thrombocytopenia. Platelet counts decreased from 225X103 /μL preoperatively to 94.5, 54.5, and 50.1X10 3/μL on postoperative days 1, 2, and 3, respectively, showing significant differences compared with the AVR group (p=0.04, p=0.16, and p=0.20, respectively). The median amount of platelet transfusion was higher in the AVR group (12.5 vs. 0 units, p=0.052). Conclusion : There was no difference in the 30-day mortality of moderate- to high-risk patients depending on whether they underwent SU-AVR or AVR. Although SU-AVR is associated with favorable cardiopulmonary bypass and cross-clamp times, it may be associated with postoperative thrombocytopenia.https://doi.org/10.5090/kjtcs.2018.51.3.172Sutureless valve replacementModerate to high risk patientPostoperative thrombocytopeniaAortic valve replacement |
| spellingShingle | Puwadon Thitivaraporn Sarun Chiramongkol Dittapol Muntham Nopporn Pornpatrtanarak Chanapong Kittayarak Jule Namchaisiri Seri Singhatanadgige Pat Ongcharit Vichai Benjacholamas Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement Korean Journal of Thoracic and Cardiovascular Surgery Sutureless valve replacement Moderate to high risk patient Postoperative thrombocytopenia Aortic valve replacement |
| title | Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement |
| title_full | Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement |
| title_fullStr | Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement |
| title_full_unstemmed | Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement |
| title_short | Thrombocytopenia in Moderate- to High-Risk Sutureless Aortic Valve Replacement |
| title_sort | thrombocytopenia in moderate to high risk sutureless aortic valve replacement |
| topic | Sutureless valve replacement Moderate to high risk patient Postoperative thrombocytopenia Aortic valve replacement |
| url | https://doi.org/10.5090/kjtcs.2018.51.3.172 |
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