Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh
Several studies have found an inverse association between vitamin D level and insulin resistance (IR) causing prediabetes and diabetes. So the current study was done to find out the association between serum vitamin D level and IR among adults with prediabetes. This cross-sectional study was carrie...
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| Format: | Article |
| Language: | English |
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Bangabandhu Sheikh Mujib Medical University
2022-03-01
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| Series: | Bangabandhu Sheikh Mujib Medical University Journal |
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| Online Access: | https://www.banglajol.info/index.php/BSMMUJ/article/view/56617 |
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| author | Murshed Ahamed Khan Md Fariduddin Shahjada Selim Mohammad Masum Alam Md Shahed Morshed Md Habibul Ghani |
| author_facet | Murshed Ahamed Khan Md Fariduddin Shahjada Selim Mohammad Masum Alam Md Shahed Morshed Md Habibul Ghani |
| author_sort | Murshed Ahamed Khan |
| collection | DOAJ |
| description |
Several studies have found an inverse association between vitamin D level and insulin resistance (IR) causing prediabetes and diabetes. So the current study was done to find out the association between serum vitamin D level and IR among adults with prediabetes. This cross-sectional study was carried out in 140 newly detected adults with prediabetes according to ADA 2018 criteria. The 25(OH) D cutoffs to define deficiency and insufficiency were used according to Endocrine Society (USA) criteria, measurement of vitamin D & insulin (fasting) was done by chemiluminescent microparticle immunoassay (CMIA). Data were analyzed using SPSS (version 22.0) and presented as table and figure. P-value ≤0.05 was considered significant. In this study, most of the population was 30 years and above (73%). The Male-female ratio was 1:7, the majority of participants came from urban areas (81%) and it was observed that there was an increasing trend of insulin resistance across increasing severity of vitamin D deficiency though it was not statistically significant (p= 0.74). In conclusion, vitamin-D deficiency/insuffi- ciency is common among individuals with prediabetes in our country, but there were no associ- ation had been found between vitamin D and insulin resistance in individuals with prediabetes
BSMMU J 2021; 14(4): 157-162
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| first_indexed | 2024-12-12T23:18:59Z |
| format | Article |
| id | doaj.art-3ee4613d1426429c98b683b12f19ade1 |
| institution | Directory Open Access Journal |
| issn | 2074-2908 2224-7750 |
| language | English |
| last_indexed | 2024-12-12T23:18:59Z |
| publishDate | 2022-03-01 |
| publisher | Bangabandhu Sheikh Mujib Medical University |
| record_format | Article |
| series | Bangabandhu Sheikh Mujib Medical University Journal |
| spelling | doaj.art-3ee4613d1426429c98b683b12f19ade12022-12-22T00:08:20ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502022-03-0114410.3329/bsmmuj.v14i4.56617Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of BangladeshMurshed Ahamed Khan0Md Fariduddin1Shahjada Selim2Mohammad Masum Alam3Md Shahed Morshed4Md Habibul Ghani5Department of Endocrinology & Metabo- lism, BSMMU, Dhaka, BangladeshDepartment of Endocrinology & Metabo- lism, BSMMU, Dhaka, BangladeshDepartment of Endocrinology & Metabo- lism, BSMMU, Dhaka, BangladeshDepartment of Biochemistry, BSMMU, Dhaka, BangladeshKurmitola General Hospital, Dhaka, BangladeshJinjira 20 beded hospital, Keranigonj, Dhaka, Bangladesh Several studies have found an inverse association between vitamin D level and insulin resistance (IR) causing prediabetes and diabetes. So the current study was done to find out the association between serum vitamin D level and IR among adults with prediabetes. This cross-sectional study was carried out in 140 newly detected adults with prediabetes according to ADA 2018 criteria. The 25(OH) D cutoffs to define deficiency and insufficiency were used according to Endocrine Society (USA) criteria, measurement of vitamin D & insulin (fasting) was done by chemiluminescent microparticle immunoassay (CMIA). Data were analyzed using SPSS (version 22.0) and presented as table and figure. P-value ≤0.05 was considered significant. In this study, most of the population was 30 years and above (73%). The Male-female ratio was 1:7, the majority of participants came from urban areas (81%) and it was observed that there was an increasing trend of insulin resistance across increasing severity of vitamin D deficiency though it was not statistically significant (p= 0.74). In conclusion, vitamin-D deficiency/insuffi- ciency is common among individuals with prediabetes in our country, but there were no associ- ation had been found between vitamin D and insulin resistance in individuals with prediabetes BSMMU J 2021; 14(4): 157-162 https://www.banglajol.info/index.php/BSMMUJ/article/view/56617Vitamin D, Prediabetes, Insulin resistance |
| spellingShingle | Murshed Ahamed Khan Md Fariduddin Shahjada Selim Mohammad Masum Alam Md Shahed Morshed Md Habibul Ghani Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh Bangabandhu Sheikh Mujib Medical University Journal Vitamin D, Prediabetes, Insulin resistance |
| title | Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh |
| title_full | Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh |
| title_fullStr | Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh |
| title_full_unstemmed | Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh |
| title_short | Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh |
| title_sort | association of vitamin d and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of bangladesh |
| topic | Vitamin D, Prediabetes, Insulin resistance |
| url | https://www.banglajol.info/index.php/BSMMUJ/article/view/56617 |
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