Lipoxin agonists: turn right! to path of resolving neutrophil
An impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2005-03-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010 |
| _version_ | 1797712593393025024 |
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| author | Pallavi R Devchand |
| author_facet | Pallavi R Devchand |
| author_sort | Pallavi R Devchand |
| collection | DOAJ |
| description | An impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation. |
| first_indexed | 2024-03-12T07:24:03Z |
| format | Article |
| id | doaj.art-3ee72e9238f24e41a422dbd6a2a98636 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T07:24:03Z |
| publishDate | 2005-03-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-3ee72e9238f24e41a422dbd6a2a986362023-09-02T22:11:09ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602005-03-01100555710.1590/S0074-02762005000900010Lipoxin agonists: turn right! to path of resolving neutrophilPallavi R DevchandAn impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010neutrophillipid mediatorsresolution of inflammation |
| spellingShingle | Pallavi R Devchand Lipoxin agonists: turn right! to path of resolving neutrophil Memorias do Instituto Oswaldo Cruz neutrophil lipid mediators resolution of inflammation |
| title | Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_full | Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_fullStr | Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_full_unstemmed | Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_short | Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_sort | lipoxin agonists turn right to path of resolving neutrophil |
| topic | neutrophil lipid mediators resolution of inflammation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010 |
| work_keys_str_mv | AT pallavirdevchand lipoxinagoniststurnrighttopathofresolvingneutrophil |