Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system

Abstract Background Radiofrequency catheter ablation is the preferred treatment choice for ventricular arrhythmias (VAs) originating from right ventricular outflow tract (RVOT) in symptomatic patients and is usually performed under fluoroscopy guidance. Zero‐fluoroscopy (ZF) ablations using 3D mappi...

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Main Authors: Ba Van Vu, Phong Dinh Phan, Linh Tran Pham, Kien Trung Hoang, Thinh Duc Do, Hung Manh Nguyen, Linh Thi Hai Ngo, Dung Tien Le, Nguyen Thao Phan, Huu Cong Nguyen, Thuc Cong Luong
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Journal of Arrhythmia
Subjects:
Online Access:https://doi.org/10.1002/joa3.12815
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author Ba Van Vu
Phong Dinh Phan
Linh Tran Pham
Kien Trung Hoang
Thinh Duc Do
Hung Manh Nguyen
Linh Thi Hai Ngo
Dung Tien Le
Nguyen Thao Phan
Huu Cong Nguyen
Thuc Cong Luong
author_facet Ba Van Vu
Phong Dinh Phan
Linh Tran Pham
Kien Trung Hoang
Thinh Duc Do
Hung Manh Nguyen
Linh Thi Hai Ngo
Dung Tien Le
Nguyen Thao Phan
Huu Cong Nguyen
Thuc Cong Luong
author_sort Ba Van Vu
collection DOAJ
description Abstract Background Radiofrequency catheter ablation is the preferred treatment choice for ventricular arrhythmias (VAs) originating from right ventricular outflow tract (RVOT) in symptomatic patients and is usually performed under fluoroscopy guidance. Zero‐fluoroscopy (ZF) ablations using 3D mapping system applied for treatment of various types of arrhythmias are trending and practiced in many centers around the world, but rarely done in Vietnam. The objective of this study was to evaluate the efficacy and safety of zero‐fluoroscopy ablation of RVOT VAs, compared with fluoroscopy‐guided ablation without a 3D electroanatomic mapping (EAM) system. Methods and Results We conducted a nonrandomized, prospective single‐center study including 114 patients with RVOT VAs that had electrocardiographic features of typical left bundle branch block, inferior axis QRS morphology, and a precordial transition ≥ V3, from May 2020 to July 2022. The patients were assigned (without randomization) to two different approaches of either zero‐fluoroscopy ablation under the guidance of the Ensite system (ZF group) or fluoroscopy‐guided ablation without a 3D EAM (fluoroscopy group) in a 1:1 ratio. After a follow‐up time of 5.0 ± 4.9 months and 6.9 ± 9.3 months in the ZF and fluoroscopy groups, respectively, the results showed a higher success rate in the fluoroscopy group than in the complete ZF group (87.3% vs 86.8%), although the difference was not statistically significant. No major complication was noted in both the groups. Conclusion ZF ablation for RVOT VAs can be done safely and effectively using the 3D electroanatomic mapping system. The results of ZF approach are comparable to that of the fluoroscopy‐guided approach without a 3D EAM system.
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spelling doaj.art-3eec2234834e43849126905063c4f2442023-05-04T05:38:07ZengWileyJournal of Arrhythmia1880-42761883-21482023-04-0139218519110.1002/joa3.12815Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping systemBa Van Vu0Phong Dinh Phan1Linh Tran Pham2Kien Trung Hoang3Thinh Duc Do4Hung Manh Nguyen5Linh Thi Hai Ngo6Dung Tien Le7Nguyen Thao Phan8Huu Cong Nguyen9Thuc Cong Luong10Cardiology Department Vietnam Military Medical University Hanoi VietnamCardiology Department Hanoi Medical University Hanoi VietnamVietnam National Heart Institute Bach Mai Hospital Hanoi VietnamCardiovascular Center E Hospital Hanoi VietnamCardiovascular Center E Hospital Hanoi VietnamCardiovascular Center E Hospital Hanoi VietnamSchool of Clinical Medicine The University of Queensland Herston Queensland AustraliaCardiovascular Center E Hospital Hanoi VietnamCardiovascular Center E Hospital Hanoi VietnamCardiovascular Center E Hospital Hanoi VietnamCardiology Department Vietnam Military Medical University Hanoi VietnamAbstract Background Radiofrequency catheter ablation is the preferred treatment choice for ventricular arrhythmias (VAs) originating from right ventricular outflow tract (RVOT) in symptomatic patients and is usually performed under fluoroscopy guidance. Zero‐fluoroscopy (ZF) ablations using 3D mapping system applied for treatment of various types of arrhythmias are trending and practiced in many centers around the world, but rarely done in Vietnam. The objective of this study was to evaluate the efficacy and safety of zero‐fluoroscopy ablation of RVOT VAs, compared with fluoroscopy‐guided ablation without a 3D electroanatomic mapping (EAM) system. Methods and Results We conducted a nonrandomized, prospective single‐center study including 114 patients with RVOT VAs that had electrocardiographic features of typical left bundle branch block, inferior axis QRS morphology, and a precordial transition ≥ V3, from May 2020 to July 2022. The patients were assigned (without randomization) to two different approaches of either zero‐fluoroscopy ablation under the guidance of the Ensite system (ZF group) or fluoroscopy‐guided ablation without a 3D EAM (fluoroscopy group) in a 1:1 ratio. After a follow‐up time of 5.0 ± 4.9 months and 6.9 ± 9.3 months in the ZF and fluoroscopy groups, respectively, the results showed a higher success rate in the fluoroscopy group than in the complete ZF group (87.3% vs 86.8%), although the difference was not statistically significant. No major complication was noted in both the groups. Conclusion ZF ablation for RVOT VAs can be done safely and effectively using the 3D electroanatomic mapping system. The results of ZF approach are comparable to that of the fluoroscopy‐guided approach without a 3D EAM system.https://doi.org/10.1002/joa3.12815right ventricular outflow tractventricular arrhythmiaszero‐fluoroscopy ablation
spellingShingle Ba Van Vu
Phong Dinh Phan
Linh Tran Pham
Kien Trung Hoang
Thinh Duc Do
Hung Manh Nguyen
Linh Thi Hai Ngo
Dung Tien Le
Nguyen Thao Phan
Huu Cong Nguyen
Thuc Cong Luong
Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
Journal of Arrhythmia
right ventricular outflow tract
ventricular arrhythmias
zero‐fluoroscopy ablation
title Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
title_full Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
title_fullStr Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
title_full_unstemmed Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
title_short Efficacy and safety of zero‐fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract: Comparison with fluoroscopy‐guided ablation without a three‐dimensional electroanatomic mapping system
title_sort efficacy and safety of zero fluoroscopy ablation of ventricular arrhythmias originating from the right ventricular outflow tract comparison with fluoroscopy guided ablation without a three dimensional electroanatomic mapping system
topic right ventricular outflow tract
ventricular arrhythmias
zero‐fluoroscopy ablation
url https://doi.org/10.1002/joa3.12815
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