Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription

Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription

Pseudorabies virus (PRV) has evolved various strategies to escape host antiviral immune responses. However, it remains unclear whether and how PRV-encoded proteins modulate the RIG-I-like receptor (RLR)-mediated signals for immune evasion. Here, we show that the PRV tegument protein UL13 functions a...

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Bibliographic Details
Main Authors: Ningning Zhao, Fan Wang, Zhengjie Kong, Yingli Shang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
pseudorabies virus (PRV)
tegument protein UL13
RIG-I
MDA5
NF-κB
Online Access:https://www.mdpi.com/1999-4915/14/7/1465

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