A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications
Chitosan is produced by deacetylating the abundant natural chitin polymer. It has been employed in a variety of applications due to its unique solubility as well as its chemical and biological properties. In addition to being biodegradable and biocompatible, it also possesses a lot of reactive amino...
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MDPI AG
2023-06-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/15/13/2820 |
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| author | Marwan A. Ibrahim Mona H. Alhalafi El-Amir M. Emam Hassan Ibrahim Rehab M. Mosaad |
| author_facet | Marwan A. Ibrahim Mona H. Alhalafi El-Amir M. Emam Hassan Ibrahim Rehab M. Mosaad |
| author_sort | Marwan A. Ibrahim |
| collection | DOAJ |
| description | Chitosan is produced by deacetylating the abundant natural chitin polymer. It has been employed in a variety of applications due to its unique solubility as well as its chemical and biological properties. In addition to being biodegradable and biocompatible, it also possesses a lot of reactive amino side groups that allow for chemical modification and the creation of a wide range of useful derivatives. The physical and chemical characteristics of chitosan, as well as how it is used in the food, environmental, and medical industries, have all been covered in a number of academic publications. Chitosan offers a wide range of possibilities in environmentally friendly textile processes because of its superior absorption and biological characteristics. Chitosan has the ability to give textile fibers and fabrics antibacterial, antiviral, anti-odor, and other biological functions. One of the most well-known and frequently used methods to create nanofibers is electrospinning. This technique is adaptable and effective for creating continuous nanofibers. In the field of biomaterials, new materials include nanofibers made of chitosan. Numerous medications, including antibiotics, chemotherapeutic agents, proteins, and analgesics for inflammatory pain, have been successfully loaded onto electro-spun nanofibers, according to recent investigations. Chitosan nanofibers have several exceptional qualities that make them ideal for use in important pharmaceutical applications, such as tissue engineering, drug delivery systems, wound dressing, and enzyme immobilization. The preparation of chitosan nanofibers, followed by a discussion of the biocompatibility and degradation of chitosan nanofibers, followed by a description of how to load the drug into the nanofibers, are the first issues highlighted by this review of chitosan nanofibers in drug delivery applications. The main uses of chitosan nanofibers in drug delivery systems will be discussed last. |
| first_indexed | 2024-03-11T01:31:09Z |
| format | Article |
| id | doaj.art-3ef267859ead422b954208876a746ba7 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-11T01:31:09Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-3ef267859ead422b954208876a746ba72023-11-18T17:20:33ZengMDPI AGPolymers2073-43602023-06-011513282010.3390/polym15132820A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential ApplicationsMarwan A. Ibrahim0Mona H. Alhalafi1El-Amir M. Emam2Hassan Ibrahim3Rehab M. Mosaad4Department of Biology, College of Science, Majmaah University, Al-Majmaah 11952, Saudi ArabiaDepartment of Chemistry, College of Science, Majmaah University, Al-Majmaah 11952, Saudi ArabiaFaculty of Applied Arts, Textile Printing, Dyeing and Finishing Department, Helwan University, Cairo 11795, EgyptPretreatment and Finishing of Cellulosic Fibers Department, Textile Research and Technology Institute, National Research Centre, Cairo 12622, EgyptDepartment of Biology, College of Science, Majmaah University, Al-Majmaah 11952, Saudi ArabiaChitosan is produced by deacetylating the abundant natural chitin polymer. It has been employed in a variety of applications due to its unique solubility as well as its chemical and biological properties. In addition to being biodegradable and biocompatible, it also possesses a lot of reactive amino side groups that allow for chemical modification and the creation of a wide range of useful derivatives. The physical and chemical characteristics of chitosan, as well as how it is used in the food, environmental, and medical industries, have all been covered in a number of academic publications. Chitosan offers a wide range of possibilities in environmentally friendly textile processes because of its superior absorption and biological characteristics. Chitosan has the ability to give textile fibers and fabrics antibacterial, antiviral, anti-odor, and other biological functions. One of the most well-known and frequently used methods to create nanofibers is electrospinning. This technique is adaptable and effective for creating continuous nanofibers. In the field of biomaterials, new materials include nanofibers made of chitosan. Numerous medications, including antibiotics, chemotherapeutic agents, proteins, and analgesics for inflammatory pain, have been successfully loaded onto electro-spun nanofibers, according to recent investigations. Chitosan nanofibers have several exceptional qualities that make them ideal for use in important pharmaceutical applications, such as tissue engineering, drug delivery systems, wound dressing, and enzyme immobilization. The preparation of chitosan nanofibers, followed by a discussion of the biocompatibility and degradation of chitosan nanofibers, followed by a description of how to load the drug into the nanofibers, are the first issues highlighted by this review of chitosan nanofibers in drug delivery applications. The main uses of chitosan nanofibers in drug delivery systems will be discussed last.https://www.mdpi.com/2073-4360/15/13/2820chitosannanofiberpreparationcharacterizationapplicationswound dressing |
| spellingShingle | Marwan A. Ibrahim Mona H. Alhalafi El-Amir M. Emam Hassan Ibrahim Rehab M. Mosaad A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications Polymers chitosan nanofiber preparation characterization applications wound dressing |
| title | A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications |
| title_full | A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications |
| title_fullStr | A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications |
| title_full_unstemmed | A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications |
| title_short | A Review of Chitosan and Chitosan Nanofiber: Preparation, Characterization, and Its Potential Applications |
| title_sort | review of chitosan and chitosan nanofiber preparation characterization and its potential applications |
| topic | chitosan nanofiber preparation characterization applications wound dressing |
| url | https://www.mdpi.com/2073-4360/15/13/2820 |
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