Exploring the Interactions of Ruthenium (II) Carbosilane Metallodendrimers and Precursors with Model Cell Membranes through a Dual Spin-Label Spin-Probe Technique Using EPR

Exploring the Interactions of Ruthenium (II) Carbosilane Metallodendrimers and Precursors with Model Cell Membranes through a Dual Spin-Label Spin-Probe Technique Using EPR

Dendrimers exhibit unique interactions with cell membranes, arising from their nanometric size and high surface area. To a great extent, these interactions define their biological activity and can be reported in situ by spin-labelling techniques. Schiff-base carbosilane ruthenium (II) metallodendrim...

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Bibliographic Details
Main Authors: Riccardo Carloni, Natalia Sanz del Olmo, Paula Ortega, Alberto Fattori, Rafael Gómez, Maria Francesca Ottaviani, Sandra García-Gallego, Michela Cangiotti, F. Javier de la Mata
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biomolecules
Subjects:
electron paramagnetic resonance
dendrimer
metallodendrimer
ruthenium
cell membrane
spin probe
cancer
Online Access:https://www.mdpi.com/2218-273X/9/10/540

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