Peroxisomal ABC Transporters: An Update

Peroxisomal ABC Transporters: An Update

ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of conserved proteins from bacteria to mammals. In humans, three members of this family are expressed in the peroxisomal membrane and belong to the subfamily D: ABCD1 (ALDP), ABCD2 (ALDRP), and ABCD3 (PMP70). These h...

Full description

Bibliographic Details
Main Authors:	Ali Tawbeh, Catherine Gondcaille, Doriane Trompier, Stéphane Savary
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	International Journal of Molecular Sciences
Subjects:	ABC transporters peroxisome adrenoleukodystrophy fatty acids
Online Access:	https://www.mdpi.com/1422-0067/22/11/6093

Similar Items

Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation
by: Ali Tawbeh, et al.
Published: (2023-12-01)

Peroxisomal defects in microglial cells induce a disease-associated microglial signature
by: Quentin Raas, et al.
Published: (2023-04-01)

Structure and Function of the <i>ABCD1</i> Variant Database: 20 Years, 940 Pathogenic Variants, and 3400 Cases of Adrenoleukodystrophy
by: Eric J. Mallack, et al.
Published: (2022-01-01)

Advanced Diagnostic System and Introduction of Newborn Screening of Adrenoleukodystrophy and Peroxisomal Disorders in Japan
by: Nobuyuki Shimozawa, et al.
Published: (2021-08-01)

Comparison of the Diagnostic Performance of C26:0-Lysophosphatidylcholine and Very Long-Chain Fatty Acids Analysis for Peroxisomal Disorders
by: Yorrick R. J. Jaspers, et al.
Published: (2020-07-01)

Evaluation of the role of the Endoplasmic Reticulum-Golgi transit in the biogenesis of peroxisomal membrane proteins in wild type and peroxisome biogenesis mutant CHO cells
by: ANDRÉS TORO, et al.
Published: (2007-01-01)

Peroxisomes in Immune Response and Inflammation
by: Francesca Di Cara, et al.
Published: (2019-08-01)

The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid[S]
by: Jingjing Liu, et al.
Published: (2012-06-01)

Anaesthesia for a child with adrenoleukodystrophy: A case report and review of the literature
by: Sien Hui Tan, et al.
Published: (2014-01-01)

Peroxisomal Disorders and Their Mouse Models Point to Essential Roles of Peroxisomes for Retinal Integrity
by: Yannick Das, et al.
Published: (2021-04-01)

A historical look using virtual microscopy: the first case report of adrenomyeloneuropathy (AMN)
by: Herbert Budka
Published: (2023-10-01)

Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy*
by: Jaspreet Singh, et al.
Published: (2009-01-01)

Peroxisomes in intracellular cholesterol transport: from basic physiology to brain pathology
by: Jian Xiao, et al.
Published: (2021-12-01)

Newborn Screening for X-Linked Adrenoleukodystrophy: The Initial Illinois Experience
by: Barbara K. Burton, et al.
Published: (2022-01-01)

Newborn Screening for X-Linked Adrenoleukodystrophy in Georgia: Experiences from a Pilot Study Screening of 51,081 Newborns
by: Patricia L. Hall, et al.
Published: (2020-10-01)

Do ABC transporters regulate plasma membrane organization?
by: Ambroise Wu, et al.
Published: (2020-07-01)

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC
by: Magdalena Karlikowska, et al.
Published: (2021-12-01)

Enhanced accumulation of oil through co-expression of fatty acid and ABC transporters in Chlamydomonas under standard growth conditions
by: Ru Chen, et al.
Published: (2022-05-01)

Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid[S]
by: Takayuki Sassa, et al.
Published: (2014-03-01)

Newborn Screening for X-Linked Adrenoleukodystrophy in Nebraska: Initial Experiences and Challenges
by: Craig V. Baker, et al.
Published: (2022-04-01)

Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy
by: Masashi Morita, et al.
Published: (2021-02-01)

Corrigendum: Adrenoleukodystrophy Newborn Screening in the Netherlands (SCAN Study): The X-Factor
by: Rinse W. Barendsen, et al.
Published: (2021-01-01)

Adrenoleukodystrophy Newborn Screening in the Netherlands (SCAN Study): The X-Factor
by: Rinse W. Barendsen, et al.
Published: (2020-06-01)

The ABC proteins family: an amazing machinery. Structure and mechanism of transport.
by: Magdalena Smolik, et al.
Published: (2020-12-01)

Transport proteins regulate the flux of metabolites and cofactors across the membrane of plants peroxisomes
by: Nicole eLinka, et al.
Published: (2012-01-01)

Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA
by: Kristin Oepen, et al.
Published: (2021-12-01)

The Overlooked Transformation Mechanisms of VLCFAs: Peroxisomal β-Oxidation
by: Qinyue Lu, et al.
Published: (2022-06-01)

Spastic paraplegia as the predominant phenotype in a cohort of Chinese patients with adrenoleukodystrophy
by: Wen‐Jiao Luo, et al.
Published: (2020-01-01)

Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner
by: Yuanyuan Bai, et al.
Published: (2023-07-01)

Peroxisomal Cofactor Transport
by: Anastasija Plett, et al.
Published: (2020-08-01)

Dysfunctional peroxisomal lipid metabolisms and their ocular manifestations
by: Chuck T. Chen, et al.
Published: (2022-09-01)

Biochemical Studies in Fibroblasts to Interpret Variants of Unknown Significance in the <i>ABCD1</i> Gene
by: Stephanie I. W. van de Stadt, et al.
Published: (2021-11-01)

Glycosphingolipids with Very Long-Chain Fatty Acids Accumulate in Fibroblasts from Adrenoleukodystrophy Patients
by: Yuko Fujiwara, et al.
Published: (2021-08-01)

Glutathione binding to the plant AtAtm3 transporter and implications for the conformational coupling of ABC transporters
by: Chengcheng Fan, et al.
Published: (2022-03-01)

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter
by: Smriti Mishra, et al.
Published: (2014-05-01)

Interactions of very long-chain saturated fatty acids with serum albumin
by: Ji-Kyung Choi, et al.
Published: (2002-07-01)

Statins Increase Mitochondrial and Peroxisomal Fatty Acid Oxidation in the Liver and Prevent Non-Alcoholic Steatohepatitis in Mice
by: Han-Sol Park, et al.
Published: (2016-04-01)

Uptake and metabolism of plasma-derived erucic acid by rat brain
by: Mikhail Y. Golovko, et al.
Published: (2006-06-01)

Exploring conformational equilibria of a heterodimeric ABC transporter
by: M Hadi Timachi, et al.
Published: (2017-01-01)

A Novel Mutation of the ABCD1 Gene in Serbian X-Adrenoleukodystrophy
by: Grkovic S, et al.
Published: (2008-01-01)