Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics
ABSTRACT This short article discusses selected scanning electron microscope and transmission electron microscope features of vasa vasorum including pericytes and basement membrane of the human saphenous vein (SV) harvested with either conventional (CON) or no-touch (NT) technique for coronary artery...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Cirurgia Cardiovascular
2023-08-01
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| Series: | Brazilian Journal of Cardiovascular Surgery |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382023000600400&tlng=en |
| _version_ | 1797739605486731264 |
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| author | Andrzej Loesch |
| author_facet | Andrzej Loesch |
| author_sort | Andrzej Loesch |
| collection | DOAJ |
| description | ABSTRACT This short article discusses selected scanning electron microscope and transmission electron microscope features of vasa vasorum including pericytes and basement membrane of the human saphenous vein (SV) harvested with either conventional (CON) or no-touch (NT) technique for coronary artery bypass grafting. Scanning electron microscope data shows the general damage to vasa vasorum of CON-SV, while the transmission electron microscope data presents ultrastructural features of the vasa in more detail. Hence there are some features suggesting pericyte involvement in the contraction of vasa blood vessels, particularly in CON-SV. Other features associated with the vasa vasorum of both CON-SV and NT-SV preparations include thickened and/or multiplied layers of the basement membrane. In some cases, multiple layers of basement membrane embrace both pericyte and vasa microvessel making an impression of a “unit” made by basement membrane-pericyte-endothelium/microvessel. It can be speculated that this structural arrangement has an effect on the contractile and/or relaxing properties of the vessels involved. Endothelial colocalization of immunoreactive inducible nitric oxide synthase and endothelin-1 can be observed (with laser confocal microscope) in some of the vasa microvessels. It can be speculated that this phenomenon, particularly of the expression of inducible nitric oxide synthase, might be related to structurally changed vasa vessels, e.g., with expanded basement membrane. Fine physiological relationships between vasa vasorum endothelium, basement membrane, pericyte, and perivascular nerves have yet to be uncovered in the detail needed for better understanding of the cells’specific effects in SV preparations for coronary artery bypass grafting. |
| first_indexed | 2024-03-12T14:00:36Z |
| format | Article |
| id | doaj.art-3ef6b09b3e414c6bb0c5774f87ef2756 |
| institution | Directory Open Access Journal |
| issn | 1678-9741 |
| language | English |
| last_indexed | 2024-03-12T14:00:36Z |
| publishDate | 2023-08-01 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| record_format | Article |
| series | Brazilian Journal of Cardiovascular Surgery |
| spelling | doaj.art-3ef6b09b3e414c6bb0c5774f87ef27562023-08-22T07:40:32ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-97412023-08-0138610.21470/1678-9741-2023-0045Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological CharacteristicsAndrzej Loeschhttps://orcid.org/0000-0002-8051-0099ABSTRACT This short article discusses selected scanning electron microscope and transmission electron microscope features of vasa vasorum including pericytes and basement membrane of the human saphenous vein (SV) harvested with either conventional (CON) or no-touch (NT) technique for coronary artery bypass grafting. Scanning electron microscope data shows the general damage to vasa vasorum of CON-SV, while the transmission electron microscope data presents ultrastructural features of the vasa in more detail. Hence there are some features suggesting pericyte involvement in the contraction of vasa blood vessels, particularly in CON-SV. Other features associated with the vasa vasorum of both CON-SV and NT-SV preparations include thickened and/or multiplied layers of the basement membrane. In some cases, multiple layers of basement membrane embrace both pericyte and vasa microvessel making an impression of a “unit” made by basement membrane-pericyte-endothelium/microvessel. It can be speculated that this structural arrangement has an effect on the contractile and/or relaxing properties of the vessels involved. Endothelial colocalization of immunoreactive inducible nitric oxide synthase and endothelin-1 can be observed (with laser confocal microscope) in some of the vasa microvessels. It can be speculated that this phenomenon, particularly of the expression of inducible nitric oxide synthase, might be related to structurally changed vasa vessels, e.g., with expanded basement membrane. Fine physiological relationships between vasa vasorum endothelium, basement membrane, pericyte, and perivascular nerves have yet to be uncovered in the detail needed for better understanding of the cells’specific effects in SV preparations for coronary artery bypass grafting.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382023000600400&tlng=enVasa VasorumPericytesBasement MembraneSaphenous VeinCABG |
| spellingShingle | Andrzej Loesch Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics Brazilian Journal of Cardiovascular Surgery Vasa Vasorum Pericytes Basement Membrane Saphenous Vein CABG |
| title | Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics |
| title_full | Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics |
| title_fullStr | Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics |
| title_full_unstemmed | Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics |
| title_short | Vasa Vasorum in Saphenous Vein for CABG: A Review of Morphological Characteristics |
| title_sort | vasa vasorum in saphenous vein for cabg a review of morphological characteristics |
| topic | Vasa Vasorum Pericytes Basement Membrane Saphenous Vein CABG |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382023000600400&tlng=en |
| work_keys_str_mv | AT andrzejloesch vasavasoruminsaphenousveinforcabgareviewofmorphologicalcharacteristics |