Multiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP).

Multiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP).

Amyloid-β precursor protein (APP) plays a central role in pathogenesis of Alzheimer's disease. APP has a short half-life and undergoes complex proteolytic processing that is highly responsive to various stimuli such as changes in cellular lipid or energy homeostasis. Cellular trafficking of APP...

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Bibliographic Details
Main Authors:	Maria Merezhko, Pranuthi Muggalla, Niko-Petteri Nykänen, Xu Yan, Prasanna Sakha, Henri J Huttunen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4059622?pdf=render

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