Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia

Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia

Stromal cell-derived factor-1 and its receptor CXCR4 are essential regulators of the neurogenesis that occurs in the adult hippocampal dentate gyrus. However, the effects of CXCR7, a new atypical receptor of stromal cell-derived factor-1, on hippocampal neurogenesis after a stroke remain largely unk...

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Bibliographic Details
Main Authors: Bing-Chao Dong, Mei-Xuan Li, Xiao-Yin Wang, Xi Cheng, Yu Wang, Ting Xiao, Jukka Jolkkonen, Chuan-Sheng Zhao, Shan-Shan Zhao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
cerebral ischemia; cognitive function; cxcr7; dendritic development; dentate gyrus; doublecortin; neurogenesis; neutralizing antibody; stroke; stromal cell-derived factor-1
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1079;epage=1085;aulast=Dong

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