Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia
IntroductionIn children, erythromelalgia is a rare chronic pain syndrome characterized by erythema, severe burning pain, and itching of affected feet. Unfortunately, there is no definitive therapy available currently.Case reportHere, we report a case of primary erythromelalgia and the treatment resp...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-05-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1143241/full |
| _version_ | 1797824094161338368 |
|---|---|
| author | Lei Zuo Ai Su Ying Shi Nan Li Shiyu Chen XiaoQiu Yang |
| author_facet | Lei Zuo Ai Su Ying Shi Nan Li Shiyu Chen XiaoQiu Yang |
| author_sort | Lei Zuo |
| collection | DOAJ |
| description | IntroductionIn children, erythromelalgia is a rare chronic pain syndrome characterized by erythema, severe burning pain, and itching of affected feet. Unfortunately, there is no definitive therapy available currently.Case reportHere, we report a case of primary erythromelalgia and the treatment response in a 10-year-old boy, whose genetic findings for mutations in the SCN9A gene were positive and skin biopsy results were diagnosed as small fiber neuropathy, while he has suffered from excruciating burning pain, itching, erythema, and recurrent infections over the past 3 years. He did not respond well to conventional treatment, and the only way to receive minimal relief was to immerse his feet in ice water. After a successful trial of spinal cord stimulation (SCS), the implantable pulse generator (IPG) was successfully implanted without complications, and it proved partial response to therapy.ConclusionThere is no specific, efficient treatment for pediatric erythromelalgia currently, but this case demonstrates neuromodulation serves as part of the multimodal regimen to treat pediatric erythromelalgia. |
| first_indexed | 2024-03-13T10:33:52Z |
| format | Article |
| id | doaj.art-3effd34b7b1648d78ffca156eac95302 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-13T10:33:52Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-3effd34b7b1648d78ffca156eac953022023-05-18T07:58:17ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-05-011410.3389/fneur.2023.11432411143241Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgiaLei ZuoAi SuYing ShiNan LiShiyu ChenXiaoQiu YangIntroductionIn children, erythromelalgia is a rare chronic pain syndrome characterized by erythema, severe burning pain, and itching of affected feet. Unfortunately, there is no definitive therapy available currently.Case reportHere, we report a case of primary erythromelalgia and the treatment response in a 10-year-old boy, whose genetic findings for mutations in the SCN9A gene were positive and skin biopsy results were diagnosed as small fiber neuropathy, while he has suffered from excruciating burning pain, itching, erythema, and recurrent infections over the past 3 years. He did not respond well to conventional treatment, and the only way to receive minimal relief was to immerse his feet in ice water. After a successful trial of spinal cord stimulation (SCS), the implantable pulse generator (IPG) was successfully implanted without complications, and it proved partial response to therapy.ConclusionThere is no specific, efficient treatment for pediatric erythromelalgia currently, but this case demonstrates neuromodulation serves as part of the multimodal regimen to treat pediatric erythromelalgia.https://www.frontiersin.org/articles/10.3389/fneur.2023.1143241/fullcase reportspinal cord stimulationpediatric erythromelalgiamultidisciplinary approachneuromodulation |
| spellingShingle | Lei Zuo Ai Su Ying Shi Nan Li Shiyu Chen XiaoQiu Yang Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia Frontiers in Neurology case report spinal cord stimulation pediatric erythromelalgia multidisciplinary approach neuromodulation |
| title | Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia |
| title_full | Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia |
| title_fullStr | Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia |
| title_full_unstemmed | Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia |
| title_short | Case report: Spinal cord stimulation in the treatment of pediatric erythromelalgia |
| title_sort | case report spinal cord stimulation in the treatment of pediatric erythromelalgia |
| topic | case report spinal cord stimulation pediatric erythromelalgia multidisciplinary approach neuromodulation |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1143241/full |
| work_keys_str_mv | AT leizuo casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia AT aisu casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia AT yingshi casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia AT nanli casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia AT shiyuchen casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia AT xiaoqiuyang casereportspinalcordstimulationinthetreatmentofpediatricerythromelalgia |