Quetiapine reverse paclitaxel-induced neuropathic pain in mice: Role of Alpha2- adrenergic receptors

Quetiapine reverse paclitaxel-induced neuropathic pain in mice: Role of Alpha2- adrenergic receptors

Objective(s): Paclitaxel-induced peripheral neuropathy is a common adverse effect of cancer chemo -therapy. This neuropathy has a profound impact on quality of life and patient’s survival. Preventing and treating paclitaxel-induced peripheral neuropathy is a major concern. First- and second-generati...

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Bibliographic Details
Main Authors: Alireza Abed, Mohammad Javad Khoshnoud, Mehdi Taghian, Mahbubeh Aliasgharzadeh, Azam Mesdaghinia
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Hyperalgesia
Mice
Neuropathic pain
Paclitaxel
Quetiapine
Yohimbine
Online Access:http://ijbms.mums.ac.ir/article_9500_84b9ae720847dd5ca90680245a5e6eee.pdf

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