A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Li et al. analyzed structural connectivity of deep brain stimulation electrodes in 50 patients suffering from obsessive-compulsive disorder operated at four centers. Connectivity to a specific tract within the anterior limb of the internal capsule was associated with optimal treatment response acros...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-16734-3 |
| _version_ | 1818428344434163712 |
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| author | Ningfei Li Juan Carlos Baldermann Astrid Kibleur Svenja Treu Harith Akram Gavin J. B. Elias Alexandre Boutet Andres M. Lozano Bassam Al-Fatly Bryan Strange Juan A. Barcia Ludvic Zrinzo Eileen Joyce Stephan Chabardes Veerle Visser-Vandewalle Mircea Polosan Jens Kuhn Andrea A. Kühn Andreas Horn |
| author_facet | Ningfei Li Juan Carlos Baldermann Astrid Kibleur Svenja Treu Harith Akram Gavin J. B. Elias Alexandre Boutet Andres M. Lozano Bassam Al-Fatly Bryan Strange Juan A. Barcia Ludvic Zrinzo Eileen Joyce Stephan Chabardes Veerle Visser-Vandewalle Mircea Polosan Jens Kuhn Andrea A. Kühn Andreas Horn |
| author_sort | Ningfei Li |
| collection | DOAJ |
| description | Li et al. analyzed structural connectivity of deep brain stimulation electrodes in 50 patients suffering from obsessive-compulsive disorder operated at four centers. Connectivity to a specific tract within the anterior limb of the internal capsule was associated with optimal treatment response across cohorts, surgeons and centers. |
| first_indexed | 2024-12-14T15:00:08Z |
| format | Article |
| id | doaj.art-3f03043ad0d44175a12a3f056b070b93 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:00:08Z |
| publishDate | 2020-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3f03043ad0d44175a12a3f056b070b932022-12-21T22:56:52ZengNature PortfolioNature Communications2041-17232020-07-0111111210.1038/s41467-020-16734-3A unified connectomic target for deep brain stimulation in obsessive-compulsive disorderNingfei Li0Juan Carlos Baldermann1Astrid Kibleur2Svenja Treu3Harith Akram4Gavin J. B. Elias5Alexandre Boutet6Andres M. Lozano7Bassam Al-Fatly8Bryan Strange9Juan A. Barcia10Ludvic Zrinzo11Eileen Joyce12Stephan Chabardes13Veerle Visser-Vandewalle14Mircea Polosan15Jens Kuhn16Andrea A. Kühn17Andreas Horn18Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Movement Disorders and Neuromodulation Unit, Department for NeurologyDepartment of Psychiatry and Psychotherapy, Department of Neurology, University of Cologne, Medical FacultyUniv. Grenoble AlpesLaboratory for Clinical Neuroscience, Centre for Biomedical Technology, Universidad Politecnica de MadridDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of NeurologyUniversity Health NetworkUniversity Health NetworkUniversity Health NetworkCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Movement Disorders and Neuromodulation Unit, Department for NeurologyLaboratory for Clinical Neuroscience, Centre for Biomedical Technology, Universidad Politecnica de MadridHospital Clínico San Carlos, Neurosurgery Department, Universidad Complutense de MadridDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of NeurologyDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of NeurologyUniv. Grenoble AlpesDepartment of Stereotactic and Functional Neurosurgery, University of CologneUniv. Grenoble AlpesDepartment of Psychiatry and Psychotherapy, Department of Neurology, University of Cologne, Medical FacultyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Movement Disorders and Neuromodulation Unit, Department for NeurologyCharité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Movement Disorders and Neuromodulation Unit, Department for NeurologyLi et al. analyzed structural connectivity of deep brain stimulation electrodes in 50 patients suffering from obsessive-compulsive disorder operated at four centers. Connectivity to a specific tract within the anterior limb of the internal capsule was associated with optimal treatment response across cohorts, surgeons and centers.https://doi.org/10.1038/s41467-020-16734-3 |
| spellingShingle | Ningfei Li Juan Carlos Baldermann Astrid Kibleur Svenja Treu Harith Akram Gavin J. B. Elias Alexandre Boutet Andres M. Lozano Bassam Al-Fatly Bryan Strange Juan A. Barcia Ludvic Zrinzo Eileen Joyce Stephan Chabardes Veerle Visser-Vandewalle Mircea Polosan Jens Kuhn Andrea A. Kühn Andreas Horn A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder Nature Communications |
| title | A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder |
| title_full | A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder |
| title_fullStr | A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder |
| title_full_unstemmed | A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder |
| title_short | A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder |
| title_sort | unified connectomic target for deep brain stimulation in obsessive compulsive disorder |
| url | https://doi.org/10.1038/s41467-020-16734-3 |
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