Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Sprog: | English |
| Udgivet: |
Nature Portfolio
2018-03-01
|
| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-018-03533-0 |