Study on relation between the phagocytic fuction of retinal pigment epithelial cells and MERTK-Ras-myosin signal pathway
AIM:To investigate relation between the phagocytic fuction of retinal pigment epithelial(RPE)cells and the signal transduction pathway of MERTK-Ras-extracellular signal regulated kinase kinase(MEK)-myosin light chain kinase(MLCK)-myosin. <p>METHODS: Cultured 3~5 passage RPE cells of C57BL/6 mo...
Main Authors: | Yu-Zhao Sun, Ruo-Shuang Zhang, Feng Gu |
---|---|
Format: | Article |
Language: | English |
Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2016-01-01
|
Series: | Guoji Yanke Zazhi |
Subjects: | |
Online Access: | http://ies.ijo.cn/cn_publish/2016/1/201601007.pdf |
Similar Items
-
Retinal atrophy, inflammation, phagocytic and metabolic disruptions develop in the MerTK-cleavage-resistant mouse model
by: Julie Enderlin, et al.
Published: (2024-04-01) -
Acute RhoA/Rho Kinase Inhibition Is Sufficient to Restore Phagocytic Capacity to Retinal Pigment Epithelium Lacking the Engulfment Receptor MerTK
by: Yingyu Mao, et al.
Published: (2021-07-01) -
Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency
by: Deborah S. Lew, et al.
Published: (2020-07-01) -
The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity
by: Christopher DeVera, et al.
Published: (2022-05-01) -
Targeting Phospholipase D Pharmacologically Prevents Phagocytic Function Loss of Retinal Pigment Epithelium Cells Exposed to High Glucose Levels
by: Vicente Bermúdez, et al.
Published: (2022-10-01)