Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization
Cardiovascular diseases remain a basic socially significant issue in most countries all over the world. Our research goal was to comparatively assess morbidity with arterial hypertension (ICD-9 codes 401–404 or ICD-10 codes I.10 –I.14) among workers involved in nuclear weaponry utilization. We exami...
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Format: | Article |
Language: | English |
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FBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”
2019-12-01
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Series: | Analiz Riska Zdorovʹû |
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Online Access: | https://journal.fcrisk.ru/eng/2019/4/10 |
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author | K.V. Briks M.V. Bannikova T.V. Azizova G.V. Zhuntova E.S. Grigor'eva |
author_facet | K.V. Briks M.V. Bannikova T.V. Azizova G.V. Zhuntova E.S. Grigor'eva |
author_sort | K.V. Briks |
collection | DOAJ |
description | Cardiovascular diseases remain a basic socially significant issue in most countries all over the world. Our research goal was to comparatively assess morbidity with arterial hypertension (ICD-9 codes 401–404 or ICD-10 codes I.10 –I.14) among workers involved in nuclear weaponry utilization. We examined an occupational cohort that included workers employed at chemical-metallurgical production of “Mayak” Production Association (PA). They were all employed in 1949–2014 and observed by medical personnel up to December 31, 2017; overall, the cohort included 10,908 people. We analyzed morbidity parameters taking into account both radiation factors (external gamma-irradiation and internal alpha-irradiation caused by incorporated plutonium) and basic non-radiation ones. Standardization was accomplished indirectly with an internal standard. Morbidity was calculated with medical statistics tools per 1,000 workers. We also assessed excess relative risk per one dose (ERR/Gy). As a result, we revealed that on December 31, 2017 2,270 arterial hypertension cases were registered in the examined cohort that included workers employed at “Mayak” PA who were involved in utilizing nuclear weaponry. We showed that standardized morbidity with arterial hypertension among workers employed at “Mayak” PA and involved in utilizing nuclear weaponry statistically significantly depended on non-radiation factors (sex, age, smoking status, attitude towards alcohol intake, body mass index, and pancreatic diabetes) and didn’t depend on total dose of external gamma-irradiation and internal alpha-irradiation absorbed in the liver. |
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institution | Directory Open Access Journal |
issn | 2308-1155 2308-1163 |
language | English |
last_indexed | 2024-12-14T15:07:32Z |
publishDate | 2019-12-01 |
publisher | FBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies” |
record_format | Article |
series | Analiz Riska Zdorovʹû |
spelling | doaj.art-3f0a7e9a46c44edca615252ce95e15402022-12-21T22:56:40ZengFBSI “Federal Scientific Center for Medical and Preventive Health Risk Management Technologies”Analiz Riska Zdorovʹû2308-11552308-11632019-12-0149310310.21668/health.risk/2019.4.10.engMorbidity with arterial hypertension among workers involved in nuclear weaponry utilizationK.V. Briks0M.V. Bannikova1T.V. Azizova2G.V. Zhuntova3E.S. Grigor'eva4The Southern Urals Biophysics Institute of the RF Federal Medical and Biological Agency, 19 Ozerskoe drive, Ozersk, 456780, Russian FederationThe Southern Urals Biophysics Institute of the RF Federal Medical and Biological Agency, 19 Ozerskoe drive, Ozersk, 456780, Russian FederationThe Southern Urals Biophysics Institute of the RF Federal Medical and Biological Agency, 19 Ozerskoe drive, Ozersk, 456780, Russian FederationThe Southern Urals Biophysics Institute of the RF Federal Medical and Biological Agency, 19 Ozerskoe drive, Ozersk, 456780, Russian FederationThe Southern Urals Biophysics Institute of the RF Federal Medical and Biological Agency, 19 Ozerskoe drive, Ozersk, 456780, Russian FederationCardiovascular diseases remain a basic socially significant issue in most countries all over the world. Our research goal was to comparatively assess morbidity with arterial hypertension (ICD-9 codes 401–404 or ICD-10 codes I.10 –I.14) among workers involved in nuclear weaponry utilization. We examined an occupational cohort that included workers employed at chemical-metallurgical production of “Mayak” Production Association (PA). They were all employed in 1949–2014 and observed by medical personnel up to December 31, 2017; overall, the cohort included 10,908 people. We analyzed morbidity parameters taking into account both radiation factors (external gamma-irradiation and internal alpha-irradiation caused by incorporated plutonium) and basic non-radiation ones. Standardization was accomplished indirectly with an internal standard. Morbidity was calculated with medical statistics tools per 1,000 workers. We also assessed excess relative risk per one dose (ERR/Gy). As a result, we revealed that on December 31, 2017 2,270 arterial hypertension cases were registered in the examined cohort that included workers employed at “Mayak” PA who were involved in utilizing nuclear weaponry. We showed that standardized morbidity with arterial hypertension among workers employed at “Mayak” PA and involved in utilizing nuclear weaponry statistically significantly depended on non-radiation factors (sex, age, smoking status, attitude towards alcohol intake, body mass index, and pancreatic diabetes) and didn’t depend on total dose of external gamma-irradiation and internal alpha-irradiation absorbed in the liver.https://journal.fcrisk.ru/eng/2019/4/10arterial hypertensionmorbidityexternal gamma-irradiationinternal alpha-irradiationoccupational irradiationcohort study“mayak” panuclear weaponry utilization |
spellingShingle | K.V. Briks M.V. Bannikova T.V. Azizova G.V. Zhuntova E.S. Grigor'eva Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization Analiz Riska Zdorovʹû arterial hypertension morbidity external gamma-irradiation internal alpha-irradiation occupational irradiation cohort study “mayak” pa nuclear weaponry utilization |
title | Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
title_full | Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
title_fullStr | Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
title_full_unstemmed | Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
title_short | Morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
title_sort | morbidity with arterial hypertension among workers involved in nuclear weaponry utilization |
topic | arterial hypertension morbidity external gamma-irradiation internal alpha-irradiation occupational irradiation cohort study “mayak” pa nuclear weaponry utilization |
url | https://journal.fcrisk.ru/eng/2019/4/10 |
work_keys_str_mv | AT kvbriks morbiditywitharterialhypertensionamongworkersinvolvedinnuclearweaponryutilization AT mvbannikova morbiditywitharterialhypertensionamongworkersinvolvedinnuclearweaponryutilization AT tvazizova morbiditywitharterialhypertensionamongworkersinvolvedinnuclearweaponryutilization AT gvzhuntova morbiditywitharterialhypertensionamongworkersinvolvedinnuclearweaponryutilization AT esgrigoreva morbiditywitharterialhypertensionamongworkersinvolvedinnuclearweaponryutilization |