Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk
Background: Diabetes is a serious risk factor for atherosclerotic cardiovascular disease and an important cause of mortality. Dyslipidemia is commonly related to type 2 diabetes, and the atherogenic index of plasma is a strong marker to predict the risk of atherosclerosis and coronary heart disease...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2023-10-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2075 |
| _version_ | 1797328444128755712 |
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| author | Hind Shakir Ahmed Melak Saleh Mohammed |
| author_facet | Hind Shakir Ahmed Melak Saleh Mohammed |
| author_sort | Hind Shakir Ahmed |
| collection | DOAJ |
| description |
Background: Diabetes is a serious risk factor for atherosclerotic cardiovascular disease and an important cause of mortality. Dyslipidemia is commonly related to type 2 diabetes, and the atherogenic index of plasma is a strong marker to predict the risk of atherosclerosis and coronary heart disease.
Objective: To study the association of atherogenic indices lipids in type 2 diabetic Iraqi patients with cardiovascular disease.
Patients and Methods: This clinical study was conducted at Baghdad Teaching Hospital/ Medical City-Baghdad from October 2022 to February 2023. Sixty type 2 diabetic patients were recruited for this study: 30 patients with cardiovascular disease and 30 without cardiovascular disease. Their ages were between 40-55 years. Another 30 healthy individuals were selected as a control group.
Results: There were considerable rises in glycemic and lipid investigations in diabetic patients with cardiovascular disease compared to those without cardiovascular disease and the control group. The present results show higher levels of lipid ratios in diabetic patients with cardiovascular disease. The results also revealed high levels of non-high-density lipoprotein cholesterol for diabetic patients with cardiovascular disease (241.8±12.24 mg/dL) versus (150.1±7.12 and 68.9±5.1 mg/dL) for those without cardiovascular disease and the controls group respectively. The atherogenic index of plasma in diabetic patients with cardiovascular disease compared to diabetic and healthy control groups were (0.8±0.09) versus (0.7±0.03 and 0.2±0.08) respectively. There was a significant correlation between the atherogenic index of plasma and anthropometric factors, glycemic and lipid profile with their ratios in diabetic patients with and without cardiovascular disease.
Conclusions: The results of this study confirm that the lipid indices are risk indicators of glycemic control with higher prognostic value than traditional factors. So, non-high-density lipoprotein cholesterol and atherogenic index of plasma can be used as a significant predictor of glycemic control.
Received: Feb., 2023
Accepted: May, 2023
Published: Oct. 2023
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| first_indexed | 2024-03-08T06:51:53Z |
| format | Article |
| id | doaj.art-3f0de07c86a140ca869e0562d1b5cce2 |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T06:51:53Z |
| publishDate | 2023-10-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-3f0de07c86a140ca869e0562d1b5cce22024-02-03T06:47:40ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572023-10-0165310.32007/jfacmedbagdad.2075Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease RiskHind Shakir Ahmed0Melak Saleh Mohammed 1University of BaghdadDepartment of Chemistry/ College of Education for Pure Science (Ibn Al Haitham)/ University of Baghdad Background: Diabetes is a serious risk factor for atherosclerotic cardiovascular disease and an important cause of mortality. Dyslipidemia is commonly related to type 2 diabetes, and the atherogenic index of plasma is a strong marker to predict the risk of atherosclerosis and coronary heart disease. Objective: To study the association of atherogenic indices lipids in type 2 diabetic Iraqi patients with cardiovascular disease. Patients and Methods: This clinical study was conducted at Baghdad Teaching Hospital/ Medical City-Baghdad from October 2022 to February 2023. Sixty type 2 diabetic patients were recruited for this study: 30 patients with cardiovascular disease and 30 without cardiovascular disease. Their ages were between 40-55 years. Another 30 healthy individuals were selected as a control group. Results: There were considerable rises in glycemic and lipid investigations in diabetic patients with cardiovascular disease compared to those without cardiovascular disease and the control group. The present results show higher levels of lipid ratios in diabetic patients with cardiovascular disease. The results also revealed high levels of non-high-density lipoprotein cholesterol for diabetic patients with cardiovascular disease (241.8±12.24 mg/dL) versus (150.1±7.12 and 68.9±5.1 mg/dL) for those without cardiovascular disease and the controls group respectively. The atherogenic index of plasma in diabetic patients with cardiovascular disease compared to diabetic and healthy control groups were (0.8±0.09) versus (0.7±0.03 and 0.2±0.08) respectively. There was a significant correlation between the atherogenic index of plasma and anthropometric factors, glycemic and lipid profile with their ratios in diabetic patients with and without cardiovascular disease. Conclusions: The results of this study confirm that the lipid indices are risk indicators of glycemic control with higher prognostic value than traditional factors. So, non-high-density lipoprotein cholesterol and atherogenic index of plasma can be used as a significant predictor of glycemic control. Received: Feb., 2023 Accepted: May, 2023 Published: Oct. 2023 https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2075Diabetes mellitus, Type 2 diabetes, Cardiovascular disease, Lipid ratios, Atherogenic index of plasma |
| spellingShingle | Hind Shakir Ahmed Melak Saleh Mohammed Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk مجلة كلية الطب Diabetes mellitus, Type 2 diabetes, Cardiovascular disease, Lipid ratios, Atherogenic index of plasma |
| title | Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk |
| title_full | Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk |
| title_fullStr | Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk |
| title_full_unstemmed | Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk |
| title_short | Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk |
| title_sort | atherogenic indices in type 2 diabetic iraqi patients and its association with cardiovascular disease risk |
| topic | Diabetes mellitus, Type 2 diabetes, Cardiovascular disease, Lipid ratios, Atherogenic index of plasma |
| url | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2075 |
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