Stimulation of c-Jun/AP-1-Activity by the Cell Cycle Inhibitor p57Kip2

p57 is a member of the Cip/Kip family of cell cycle inhibitors which restrict the eukaryotic cell cycle by binding to and inhibiting cyclin/CDK complexes. They are considered as tumor suppressors and inactivating genomic mutations of p57 are associated with human overgrowth disorders. Increasing evi...

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Bibliographic Details
Main Authors: Michael Keith Kullmann, Fragka Pegka, Christian Ploner, Ludger Hengst
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.664609/full