Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study

Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study

Abstract Background Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management. Previous research shows the tendency of dexmedetomidine and propofol in improving long-term outcome of SAH patients, whereas midaz...

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Bibliographic Details
Main Authors: Yi-Chen Li, Rong Wang, Ji-Ye A, Run-Bin Sun, Shi-Jie Na, Tao Liu, Xuan-Sheng Ding, Wei-Hong Ge
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Anesthesiology
Subjects:
Subarachnoid hemorrhage
Sedation
Midazolam
Propofol
Dexmedetomidine
Metabolomics
Online Access:https://doi.org/10.1186/s12871-022-01574-z

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