Dyslipoproteinemia in Gestosis in Early Puerperium
Objective: to study the blood atherogenic potential in women with gestosis in early puerperium to assess a risk of cardiovascular diseases. Subjects and methods: The concentrations of triglycerides, total cholesterol, and cholesterols of high-density lipoprotein, low-density lipoprotein, and very lo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2008-10-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/654 |
| _version_ | 1797874329653870592 |
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| author | L. N. Shcherbakova B. F. Nazarov L. V. Molchanova |
| author_facet | L. N. Shcherbakova B. F. Nazarov L. V. Molchanova |
| author_sort | L. N. Shcherbakova |
| collection | DOAJ |
| description | Objective: to study the blood atherogenic potential in women with gestosis in early puerperium to assess a risk of cardiovascular diseases. Subjects and methods: The concentrations of triglycerides, total cholesterol, and cholesterols of high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein were measured in 32 patients aged 25—30 years in early puerperium. The data of examining women with gestoses (Group 3) were compared with the results of examining those after physiological pregnancy delivered both during vaginal delivery (Group 1) and via cesarean section (Group 2). Results and discussion. The puerperas with gestosis had significant hypertriglyceridemia and hyperbetacholesterolemia throughout the follow-up. There were no significant abnormal concentrations of low-density lipoproteins. In gestosis and after cesarean section, there was an almost double fall in the blood concentration of high-density lipoproteins to the level that assigned these patients to a group at risk for cardiovascular diseases. In these patients, the cholesterol atherogenicity coefficient was drastically increased. A moderate increase in the blood atherogenic potential in early puerperium was noted both during normal pregnancy and at normal labor. Conclusion. Concomitance of hypertriglyceridemia and hyperprebetacholesrerolemia with the low concentration of high-density lipoproteins suggests that after prior gestosis, cardiovascular complications may develop, presenting a high death risk. It is concluded that it is necessary to monitor the blood lipoprotein spectrum during gestation and puerperium and atherogenic dyslipoproteinemia can be corrected in case of its detection. Key words: gestosis, puerperium, dyslipoproteinemia, hypertriglyceridemia, hyperprebetacholesterolemia. |
| first_indexed | 2024-04-10T01:30:18Z |
| format | Article |
| id | doaj.art-3f134fb8d4ce49d6a522784cbd91d372 |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2024-04-10T01:30:18Z |
| publishDate | 2008-10-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-3f134fb8d4ce49d6a522784cbd91d3722023-03-13T09:32:49ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102008-10-014510.15360/1813-9779-2008-5-31654Dyslipoproteinemia in Gestosis in Early PuerperiumL. N. ShcherbakovaB. F. NazarovL. V. MolchanovaObjective: to study the blood atherogenic potential in women with gestosis in early puerperium to assess a risk of cardiovascular diseases. Subjects and methods: The concentrations of triglycerides, total cholesterol, and cholesterols of high-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein were measured in 32 patients aged 25—30 years in early puerperium. The data of examining women with gestoses (Group 3) were compared with the results of examining those after physiological pregnancy delivered both during vaginal delivery (Group 1) and via cesarean section (Group 2). Results and discussion. The puerperas with gestosis had significant hypertriglyceridemia and hyperbetacholesterolemia throughout the follow-up. There were no significant abnormal concentrations of low-density lipoproteins. In gestosis and after cesarean section, there was an almost double fall in the blood concentration of high-density lipoproteins to the level that assigned these patients to a group at risk for cardiovascular diseases. In these patients, the cholesterol atherogenicity coefficient was drastically increased. A moderate increase in the blood atherogenic potential in early puerperium was noted both during normal pregnancy and at normal labor. Conclusion. Concomitance of hypertriglyceridemia and hyperprebetacholesrerolemia with the low concentration of high-density lipoproteins suggests that after prior gestosis, cardiovascular complications may develop, presenting a high death risk. It is concluded that it is necessary to monitor the blood lipoprotein spectrum during gestation and puerperium and atherogenic dyslipoproteinemia can be corrected in case of its detection. Key words: gestosis, puerperium, dyslipoproteinemia, hypertriglyceridemia, hyperprebetacholesterolemia.https://www.reanimatology.com/rmt/article/view/654 |
| spellingShingle | L. N. Shcherbakova B. F. Nazarov L. V. Molchanova Dyslipoproteinemia in Gestosis in Early Puerperium Общая реаниматология |
| title | Dyslipoproteinemia in Gestosis in Early Puerperium |
| title_full | Dyslipoproteinemia in Gestosis in Early Puerperium |
| title_fullStr | Dyslipoproteinemia in Gestosis in Early Puerperium |
| title_full_unstemmed | Dyslipoproteinemia in Gestosis in Early Puerperium |
| title_short | Dyslipoproteinemia in Gestosis in Early Puerperium |
| title_sort | dyslipoproteinemia in gestosis in early puerperium |
| url | https://www.reanimatology.com/rmt/article/view/654 |
| work_keys_str_mv | AT lnshcherbakova dyslipoproteinemiaingestosisinearlypuerperium AT bfnazarov dyslipoproteinemiaingestosisinearlypuerperium AT lvmolchanova dyslipoproteinemiaingestosisinearlypuerperium |