Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis
Abstract Background Lung ultrasound (LUS) is recommended as a reliable diagnostic alternative to chest X-ray (CXR) for detecting pneumonia in children. Methods PubMed, Embase, and Cochrane Library databases were used to identify eligible studies from their inception until April 2023. The investigate...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Italian Journal of Pediatrics |
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| Online Access: | https://doi.org/10.1186/s13052-024-01583-3 |
| _version_ | 1797276390379225088 |
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| author | Yalong Yang Yuexuan Wu Wen Zhao |
| author_facet | Yalong Yang Yuexuan Wu Wen Zhao |
| author_sort | Yalong Yang |
| collection | DOAJ |
| description | Abstract Background Lung ultrasound (LUS) is recommended as a reliable diagnostic alternative to chest X-ray (CXR) for detecting pneumonia in children. Methods PubMed, Embase, and Cochrane Library databases were used to identify eligible studies from their inception until April 2023. The investigated diagnostic parameters included sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic curves (AUC). Results Twenty-six studies involving 3,401 children were selected for meta-analysis. The sensitivity, specificity, PLR, NLR, DOR, and AUC of LUS for detecting pneumonia in children were 0.95, 0.92, 12.31, 0.05, 108.53, and 0.98, respectively, while the sensitivity, specificity, PLR, NLR, DOR, and AUC of CXR were 0.92, 0.93, 24.63, 0.08, 488.54, and 0.99, respectively. The sensitivity of LUS was higher than that of CXR for detecting pneumonia in children (ratio: 1.03; 95% CI: 1.01–1.06; P = 0.018), whereas the DOR of LUS was significantly lower than that of CXR (ratio: 0.22; 95% CI: 0.06–0.85; P = 0.028). Conclusions This study found that the diagnostic performance of LUS was comparable to that of CXR for detecting pneumonia, and the sensitivity of LUS was superior to that of CXR. |
| first_indexed | 2024-03-07T15:27:37Z |
| format | Article |
| id | doaj.art-3f176ea66f1d4c50839808f7f70c4651 |
| institution | Directory Open Access Journal |
| issn | 1824-7288 |
| language | English |
| last_indexed | 2024-03-07T15:27:37Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj.art-3f176ea66f1d4c50839808f7f70c46512024-03-05T16:36:47ZengBMCItalian Journal of Pediatrics1824-72882024-01-0150111110.1186/s13052-024-01583-3Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysisYalong Yang0Yuexuan Wu1Wen Zhao2Department of Pediatrics, General Hospital of Ningxia Medical UniversityDepartment of Pediatrics, General Hospital of Ningxia Medical UniversityNingxia Medical UniversityAbstract Background Lung ultrasound (LUS) is recommended as a reliable diagnostic alternative to chest X-ray (CXR) for detecting pneumonia in children. Methods PubMed, Embase, and Cochrane Library databases were used to identify eligible studies from their inception until April 2023. The investigated diagnostic parameters included sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic curves (AUC). Results Twenty-six studies involving 3,401 children were selected for meta-analysis. The sensitivity, specificity, PLR, NLR, DOR, and AUC of LUS for detecting pneumonia in children were 0.95, 0.92, 12.31, 0.05, 108.53, and 0.98, respectively, while the sensitivity, specificity, PLR, NLR, DOR, and AUC of CXR were 0.92, 0.93, 24.63, 0.08, 488.54, and 0.99, respectively. The sensitivity of LUS was higher than that of CXR for detecting pneumonia in children (ratio: 1.03; 95% CI: 1.01–1.06; P = 0.018), whereas the DOR of LUS was significantly lower than that of CXR (ratio: 0.22; 95% CI: 0.06–0.85; P = 0.028). Conclusions This study found that the diagnostic performance of LUS was comparable to that of CXR for detecting pneumonia, and the sensitivity of LUS was superior to that of CXR.https://doi.org/10.1186/s13052-024-01583-3Lung ultrasoundChest X-rayPneumoniaChildrenMeta-analysis |
| spellingShingle | Yalong Yang Yuexuan Wu Wen Zhao Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis Italian Journal of Pediatrics Lung ultrasound Chest X-ray Pneumonia Children Meta-analysis |
| title | Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis |
| title_full | Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis |
| title_fullStr | Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis |
| title_full_unstemmed | Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis |
| title_short | Comparison of lung ultrasound and chest radiography for detecting pneumonia in children: a systematic review and meta-analysis |
| title_sort | comparison of lung ultrasound and chest radiography for detecting pneumonia in children a systematic review and meta analysis |
| topic | Lung ultrasound Chest X-ray Pneumonia Children Meta-analysis |
| url | https://doi.org/10.1186/s13052-024-01583-3 |
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