Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence
Background Increased physical activity (PA) may mitigate the negative cardiovascular health effects of sedentary behavior in adolescents. However, the relationship of PA and sedentary time from childhood with cardiac function in adolescence remains underexplored. Therefore, we investigated the assoc...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-03-01
|
| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.031837 |
| _version_ | 1797257377655816192 |
|---|---|
| author | Eero A. Haapala Marja H. Leppänen Earric Lee Kai Savonen Jari A. Laukkanen Mika Kähönen Soren Brage Timo A. Lakka |
| author_facet | Eero A. Haapala Marja H. Leppänen Earric Lee Kai Savonen Jari A. Laukkanen Mika Kähönen Soren Brage Timo A. Lakka |
| author_sort | Eero A. Haapala |
| collection | DOAJ |
| description | Background Increased physical activity (PA) may mitigate the negative cardiovascular health effects of sedentary behavior in adolescents. However, the relationship of PA and sedentary time from childhood with cardiac function in adolescence remains underexplored. Therefore, we investigated the associations of cumulative sedentary time and PA from childhood to adolescence with cardiac function in adolescence. Methods and Results Participants were 153 adolescents (69 girls) who were aged 6 to 8 years at baseline, 8 to 10 years at 2‐year follow‐up, and 15 to 17 years at 8‐year follow‐up. Cumulative sedentary time and PA exposure between baseline and 2‐year follow‐up and between baseline and 8‐year follow‐up were measured using a combined accelerometer and heart rate monitor. Cardiac function was assessed using impedance cardiography at 8‐year follow‐up. The data were analyzed using linear regression analyses adjusted for age and sex. Cumulative moderate to vigorous PA (standardized regression coefficient [β]=−0.323 [95% CI, −0.527 to −0.119]) and vigorous PA (β=−0.295 [95% CI, −0.508 to −0.083]) from baseline to 8‐year follow‐up were inversely associated with cardiac work at 8‐year follow‐up. Conversely, cumulative sedentary time had a positive association (β=0.245 [95% CI, 0.092−0.398]). Cumulative vigorous PA from baseline to 8‐year follow‐up was inversely associated with cardiac work index at 8‐year follow‐up (β=−0.218 [95% CI, −0.436 to 0.000]). Conclusions Higher levels of sedentary time and lower levels of PA during childhood were associated with higher cardiac work in adolescence, highlighting the importance of increasing PA and reducing sedentary time from childhood. |
| first_indexed | 2024-04-24T22:36:41Z |
| format | Article |
| id | doaj.art-3f18335dd9a547498553816415ea9ce4 |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-24T22:36:41Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-3f18335dd9a547498553816415ea9ce42024-03-19T10:07:06ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-03-0113610.1161/JAHA.123.031837Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in AdolescenceEero A. Haapala0Marja H. Leppänen1Earric Lee2Kai Savonen3Jari A. Laukkanen4Mika Kähönen5Soren Brage6Timo A. Lakka7Faculty of Sport and Health Sciences University of Jyväskylä Jyväskylä FinlandInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio FinlandFaculty of Sport and Health Sciences University of Jyväskylä Jyväskylä FinlandFoundation for Research in Health Exercise and Nutrition Kuopio Research Institute of Exercise Medicine Kuopio FinlandInstitute of Public Health and Clinical Nutrition University of Eastern Finland Kuopio FinlandDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology Tampere University Tampere FinlandMRC Epidemiology Unit University of Cambridge School of Clinical Medicine Cambridge United KingdomInstitute of Biomedicine, School of Medicine University of Eastern Finland Kuopio FinlandBackground Increased physical activity (PA) may mitigate the negative cardiovascular health effects of sedentary behavior in adolescents. However, the relationship of PA and sedentary time from childhood with cardiac function in adolescence remains underexplored. Therefore, we investigated the associations of cumulative sedentary time and PA from childhood to adolescence with cardiac function in adolescence. Methods and Results Participants were 153 adolescents (69 girls) who were aged 6 to 8 years at baseline, 8 to 10 years at 2‐year follow‐up, and 15 to 17 years at 8‐year follow‐up. Cumulative sedentary time and PA exposure between baseline and 2‐year follow‐up and between baseline and 8‐year follow‐up were measured using a combined accelerometer and heart rate monitor. Cardiac function was assessed using impedance cardiography at 8‐year follow‐up. The data were analyzed using linear regression analyses adjusted for age and sex. Cumulative moderate to vigorous PA (standardized regression coefficient [β]=−0.323 [95% CI, −0.527 to −0.119]) and vigorous PA (β=−0.295 [95% CI, −0.508 to −0.083]) from baseline to 8‐year follow‐up were inversely associated with cardiac work at 8‐year follow‐up. Conversely, cumulative sedentary time had a positive association (β=0.245 [95% CI, 0.092−0.398]). Cumulative vigorous PA from baseline to 8‐year follow‐up was inversely associated with cardiac work index at 8‐year follow‐up (β=−0.218 [95% CI, −0.436 to 0.000]). Conclusions Higher levels of sedentary time and lower levels of PA during childhood were associated with higher cardiac work in adolescence, highlighting the importance of increasing PA and reducing sedentary time from childhood.https://www.ahajournals.org/doi/10.1161/JAHA.123.031837exerciseheart functionpediatricssedentary behavior |
| spellingShingle | Eero A. Haapala Marja H. Leppänen Earric Lee Kai Savonen Jari A. Laukkanen Mika Kähönen Soren Brage Timo A. Lakka Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease exercise heart function pediatrics sedentary behavior |
| title | Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence |
| title_full | Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence |
| title_fullStr | Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence |
| title_full_unstemmed | Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence |
| title_short | Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence |
| title_sort | accumulating sedentary time and physical activity from childhood to adolescence and cardiac function in adolescence |
| topic | exercise heart function pediatrics sedentary behavior |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.123.031837 |
| work_keys_str_mv | AT eeroahaapala accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT marjahleppanen accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT earriclee accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT kaisavonen accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT jarialaukkanen accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT mikakahonen accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT sorenbrage accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence AT timoalakka accumulatingsedentarytimeandphysicalactivityfromchildhoodtoadolescenceandcardiacfunctioninadolescence |