Molecular mechanisms underlying microglial sensing and phagocytosis in synaptic pruning

Molecular mechanisms underlying microglial sensing and phagocytosis in synaptic pruning

Microglia are the main non-neuronal cells in the central nervous system that have important roles in brain development and functional connectivity of neural circuits. In brain physiology, highly dynamic microglial processes are facilitated to sense the surrounding environment and stimuli. Once the b...

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Bibliographic Details
Main Authors: Anran Huo, Jiali Wang, Qi Li, Mengqi Li, Yuwan Qi, Qiao Yin, Weifeng Luo, Jijun Shi, Qifei Cong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
complement; immune signals; microglia; molecular signal; synapse elimination; synapse formation; synapse refinement; synaptic pruning
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=6;spage=1284;epage=1290;aulast=Huo

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