MicroRNA-511-3p Mediated Modulation of the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Controls LPS-Induced Inflammatory Responses in Human Monocyte Derived DCs

MicroRNA-511-3p Mediated Modulation of the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Controls LPS-Induced Inflammatory Responses in Human Monocyte Derived DCs

The peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription factor expressed in dendritic cells (DCs), where it exerts anti-inflammatory responses against TLR4-induced inflammation. Recently, microRNA-511 (miR-511) has also emerged as a key player in controlling...

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Bibliographic Details
Main Authors: Dennis Awuah, Alisa Ruisinger, Meshal Alobaid, Chidimma Mbadugha, Amir M. Ghaemmaghami
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Immuno
Subjects:
dendritic cells
miR-511-3p
RNAi
PPARγ
inflammation
indoleamine 2,3 dioxygenase
Online Access:https://www.mdpi.com/2673-5601/2/1/8

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