Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria

Objectives This study focus on the preparation of the compound nanoscale layers of Zinc oxide (ZnO) with naproxen and cephalexin. Methods Ion exchange technique via sol-gel method synthesised under aqueous environment, resulted in the formation of inorganic organic characteristics of nanohybrid by u...

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Main Authors: Maryam Sabah Al-Hisnawi, Mohammed Abdulla Jabor
Format: Article
Language:English
Published: Nab'a Al-Hayat Foundation for Medical Sciences and Health Care - Press 2016-01-01
Series:Journal of Contemporary Medical Sciences
Subjects:
Online Access:http://jocms.org/index.php/jcms/article/view/46
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author Maryam Sabah Al-Hisnawi
Mohammed Abdulla Jabor
author_facet Maryam Sabah Al-Hisnawi
Mohammed Abdulla Jabor
author_sort Maryam Sabah Al-Hisnawi
collection DOAJ
description Objectives This study focus on the preparation of the compound nanoscale layers of Zinc oxide (ZnO) with naproxen and cephalexin. Methods Ion exchange technique via sol-gel method synthesised under aqueous environment, resulted in the formation of inorganic organic characteristics of nanohybrid by using X-ray diffraction (XRD) method and study antibacterial activity of hybrid and free compound against some bacteria. Results The powder X-ray diffraction showed new level for nanohybrid compounds differ from free compounds. The antibacterial results show more nanohybrid compounds concentration increased its effectiveness against bacteria, the greater the concentration of the compound greater is the increase in its effectiveness against bacteria inhibitory. Conclusions The possibility of the bind of drugs (Cephalexin and Naproxen) in the preparation of nanohybrid-ZnO compound and the use of nanocompounds as antibacterial agent in better treatment of pathogenic bacteria. And this nanocompound is more efficient from free compounds.
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spelling doaj.art-3f211adf680343ae8e39b26aa64fa8652022-12-22T03:17:06ZengNab'a Al-Hayat Foundation for Medical Sciences and Health Care - PressJournal of Contemporary Medical Sciences2413-05162016-01-0114161934Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteriaMaryam Sabah Al-Hisnawi0Mohammed Abdulla Jabor1Babylon University, College of Science, Department of BiotechnologyBabylon University, College of Science, Department of BiotechnologyObjectives This study focus on the preparation of the compound nanoscale layers of Zinc oxide (ZnO) with naproxen and cephalexin. Methods Ion exchange technique via sol-gel method synthesised under aqueous environment, resulted in the formation of inorganic organic characteristics of nanohybrid by using X-ray diffraction (XRD) method and study antibacterial activity of hybrid and free compound against some bacteria. Results The powder X-ray diffraction showed new level for nanohybrid compounds differ from free compounds. The antibacterial results show more nanohybrid compounds concentration increased its effectiveness against bacteria, the greater the concentration of the compound greater is the increase in its effectiveness against bacteria inhibitory. Conclusions The possibility of the bind of drugs (Cephalexin and Naproxen) in the preparation of nanohybrid-ZnO compound and the use of nanocompounds as antibacterial agent in better treatment of pathogenic bacteria. And this nanocompound is more efficient from free compounds.http://jocms.org/index.php/jcms/article/view/46nanohybrid, biological activities, zinc oxide, naproxin, cephalexin
spellingShingle Maryam Sabah Al-Hisnawi
Mohammed Abdulla Jabor
Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
Journal of Contemporary Medical Sciences
nanohybrid, biological activities, zinc oxide, naproxin, cephalexin
title Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
title_full Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
title_fullStr Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
title_full_unstemmed Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
title_short Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria
title_sort preparation of nanohybrid compound from the drugs naproxen and cephalexin with zinc oxide and studying biological activities against aeromonas bacteria
topic nanohybrid, biological activities, zinc oxide, naproxin, cephalexin
url http://jocms.org/index.php/jcms/article/view/46
work_keys_str_mv AT maryamsabahalhisnawi preparationofnanohybridcompoundfromthedrugsnaproxenandcephalexinwithzincoxideandstudyingbiologicalactivitiesagainstaeromonasbacteria
AT mohammedabdullajabor preparationofnanohybridcompoundfromthedrugsnaproxenandcephalexinwithzincoxideandstudyingbiologicalactivitiesagainstaeromonasbacteria