Nuclear factor-kappaB mediates the survival of rat kidney cells after cadmium exposure via promoting autophagy and inhibiting apoptosis

Nuclear factor-kappaB mediates the survival of rat kidney cells after cadmium exposure via promoting autophagy and inhibiting apoptosis

Cadmium (Cd) is a heavy metal pollutant in the environment, and the kidney is one of the target organs after Cd exposure. Previous studies have shown that apoptosis and autophagy disorders are the main mechanisms of Cd-induced nephrotoxicity in rats. As a transcription factor that balances cell surv...

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Bibliographic Details
Main Authors: Zhonggui Gong, Wenjing Liu, Ruilong Song, Wenxuan Dong, Kanglei Zhang, Jiahui Li, Hui Zou, Jiaqiao Zhu, Yonggang Ma, Gang Liu, Zongping Liu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Nuclear factor-kappaB
NRK-52E
Apoptosis
Autophagy
Nephrotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322013057

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