Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Gene expression profiling of peripheral blood mononuclear cells (PBMCs) has revealed a crucial role for type I interferon (IFN) in the pathogenesis of systemic lupus erythematosus (SLE). However, it is unclear how particular leucocyte subsets contribute to the overall type I IFN signature of PBMCs a...

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Bibliographic Details
Main Authors: Chieko Kyogoku, Biljana Smiljanovic, Joachim R Grün, Robert Biesen, Ursula Schulte-Wrede, Thomas Häupl, Falk Hiepe, Tobias Alexander, Andreas Radbruch, Andreas Grützkau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877094?pdf=render

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