Do late preterm twins face an increased neonatal morbidity compared with singletons?
OBJECTIVE Late preterm infants (born between 34 0/7 and 36 6/7 weeks of gestation) have been shown to have a higher morbidity and mortality than term infants. Furthermore, twins, both term and preterm, have a higher neonatal morbidity than singletons. The aim of our study was to examine...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2018-01-01
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| Series: | Swiss Medical Weekly |
| Subjects: | |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/2431 |
| _version_ | 1797979660431130624 |
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| author | Jarmila A. Zdanowicz Eliane Sommer Luigi Raio Mathias Nelle Roland Gerull |
| author_facet | Jarmila A. Zdanowicz Eliane Sommer Luigi Raio Mathias Nelle Roland Gerull |
| author_sort | Jarmila A. Zdanowicz |
| collection | DOAJ |
| description |
OBJECTIVE
Late preterm infants (born between 34 0/7 and 36 6/7 weeks of gestation) have been shown to have a higher morbidity and mortality than term infants. Furthermore, twins, both term and preterm, have a higher neonatal morbidity than singletons. The aim of our study was to examine if late preterm twins consequently have twice the neonatal morbidity when both risk factors prematurity and multiple pregnancy are present.
STUDY DESIGN
A retrospective single-centre study was conducted to compare neonatal outcome of late preterm singletons and late preterm twins born between 34 0/7 and 36 6/7 weeks of gestation as well as term twins with a gestational age from 37 0/7 to 41 6/7 weeks. Primary outcome was length of hospitalisation. Secondary outcome was neonatal morbidity.
RESULTS
A total of 845 infants were included. Late preterm twins (n = 243) were hospitalised significantly longer than term twins (n = 107) (13.5 ± 8.0 vs 6.29 ± 2.0 days, p <0.001) and late preterm singletons (n = 495) (13.5 ± 8.0 vs 12.6 ± 8.6 days, p = 0.011). Hyperbilirubinaemia occurred significantly more often in late preterm singletons than in late preterm twins (49.7 vs 29.2%; p<0.001). Otherwise, no significant differences were detected regarding neonatal morbidities or mortality of late preterm singletons and late preterm twins. Late preterm twins had a significantly higher incidence of most morbidities than term twins.
CONCLUSION
Late preterm twins are hospitalised significantly longer than similar-aged singletons, but have otherwise similar neonatal morbidities. Hyperbilirubinaemia is less frequent in late preterm twins than late preterm singletons.
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| first_indexed | 2024-04-11T05:42:25Z |
| format | Article |
| id | doaj.art-3f2845ff32334b7d946fa3028e3791a8 |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-11T05:42:25Z |
| publishDate | 2018-01-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-3f2845ff32334b7d946fa3028e3791a82022-12-22T04:42:30ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972018-01-01148010210.4414/smw.2018.14581Do late preterm twins face an increased neonatal morbidity compared with singletons?Jarmila A. Zdanowicz0Eliane Sommer1Luigi Raio2Mathias Nelle3Roland Gerull4Department of Obstetrics and Gynaecology, Bern University Hospital, University of Bern, SwitzerlandDepartment of Paediatrics, Division of Neonatology, Bern University Hospital, University of Bern, SwitzerlandDepartment of Obstetrics and Gynaecology, Bern University Hospital, University of Bern, SwitzerlandDepartment of Paediatrics, Division of Neonatology, Bern University Hospital, University of Bern, SwitzerlandDepartment of Paediatrics, Division of Neonatology, Bern University Hospital, University of Bern, Switzerland; University of Basel Children’s Hospital (UKBB), Neonatology, Basel, Switzerland OBJECTIVE Late preterm infants (born between 34 0/7 and 36 6/7 weeks of gestation) have been shown to have a higher morbidity and mortality than term infants. Furthermore, twins, both term and preterm, have a higher neonatal morbidity than singletons. The aim of our study was to examine if late preterm twins consequently have twice the neonatal morbidity when both risk factors prematurity and multiple pregnancy are present. STUDY DESIGN A retrospective single-centre study was conducted to compare neonatal outcome of late preterm singletons and late preterm twins born between 34 0/7 and 36 6/7 weeks of gestation as well as term twins with a gestational age from 37 0/7 to 41 6/7 weeks. Primary outcome was length of hospitalisation. Secondary outcome was neonatal morbidity. RESULTS A total of 845 infants were included. Late preterm twins (n = 243) were hospitalised significantly longer than term twins (n = 107) (13.5 ± 8.0 vs 6.29 ± 2.0 days, p <0.001) and late preterm singletons (n = 495) (13.5 ± 8.0 vs 12.6 ± 8.6 days, p = 0.011). Hyperbilirubinaemia occurred significantly more often in late preterm singletons than in late preterm twins (49.7 vs 29.2%; p<0.001). Otherwise, no significant differences were detected regarding neonatal morbidities or mortality of late preterm singletons and late preterm twins. Late preterm twins had a significantly higher incidence of most morbidities than term twins. CONCLUSION Late preterm twins are hospitalised significantly longer than similar-aged singletons, but have otherwise similar neonatal morbidities. Hyperbilirubinaemia is less frequent in late preterm twins than late preterm singletons. https://www.smw.ch/index.php/smw/article/view/2431late pretermtermtwinssingletonsmorbiditymortality |
| spellingShingle | Jarmila A. Zdanowicz Eliane Sommer Luigi Raio Mathias Nelle Roland Gerull Do late preterm twins face an increased neonatal morbidity compared with singletons? Swiss Medical Weekly late preterm term twins singletons morbidity mortality |
| title | Do late preterm twins face an increased neonatal morbidity compared with singletons? |
| title_full | Do late preterm twins face an increased neonatal morbidity compared with singletons? |
| title_fullStr | Do late preterm twins face an increased neonatal morbidity compared with singletons? |
| title_full_unstemmed | Do late preterm twins face an increased neonatal morbidity compared with singletons? |
| title_short | Do late preterm twins face an increased neonatal morbidity compared with singletons? |
| title_sort | do late preterm twins face an increased neonatal morbidity compared with singletons |
| topic | late preterm term twins singletons morbidity mortality |
| url | https://www.smw.ch/index.php/smw/article/view/2431 |
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