Effect of a combination of pea protein, grape seed extract and lactic acid in an in vivo model of bacterial vaginosis

Effect of a combination of pea protein, grape seed extract and lactic acid in an in vivo model of bacterial vaginosis

Abstract Bacterial vaginosis (BV) is a common vaginal dysbiosis characterized by a malodorous discharge and irritation. The imbalance of the vaginal microbiota plays a key role in the development of BV. It has been demonstrated that Gardnerella vaginalis (GV), a facultative anaerobic bacillus, is in...

Full description

Bibliographic Details
Main Authors:	Marika Lanza, Sarah Adriana Scuderi, Anna Paola Capra, Giovanna Casili, Alessia Filippone, Michela Campolo, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-02-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-28957-7

Similar Items

A New Approach for the Treatment of Recurrent Vulvovaginal Candidiasis with a Combination of Pea Protein, Grape Seed Extract, and Lactic Acid Assessed In Vivo
by: Irene Paterniti, et al.
Published: (2022-11-01)

Evaluation of the Efficacy of Xyloglucan, Pea Protein and <i>Opuntia ficus-indica</i> Extract in a Preclinical Model of Psoriasis
by: Alessia Filippone, et al.
Published: (2023-02-01)

Effect of a Product Containing Xyloglucan and Pea Protein on a Murine Model of Atopic Dermatitis
by: Michela Campolo, et al.
Published: (2020-05-01)

A Combination of Xyloglucan, Pea Protein and Chia Seed Ameliorates Intestinal Barrier Integrity and Mucosa Functionality in a Rat Model of Constipation-Predominant Irritable Bowel Syndrome
by: Alessia Filippone, et al.
Published: (2022-11-01)

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate
by: Alessia Filippone, et al.
Published: (2020-04-01)

Evaluating the Protective Properties of a Xyloglucan-Based Nasal Spray in a Mouse Model of Allergic Rhinitis
by: Marika Lanza, et al.
Published: (2021-09-01)

Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
by: Giovanna Casili, et al.
Published: (2020-02-01)

Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation
by: Giovanna Casili, et al.
Published: (2020-10-01)

PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis
by: Michela Campolo, et al.
Published: (2021-04-01)

Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine
by: Marika Lanza, et al.
Published: (2022-04-01)

Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome
by: Sarah Adriana Scuderi, et al.
Published: (2020-11-01)

The Transcription Factor Nrf2 Mediates the Effects of <i>Antrodia camphorata</i> Extract on Neuropathological Changes in a Mouse Model of Parkinson’s Disease
by: Marika Lanza, et al.
Published: (2023-05-01)

Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the <i>N</i>-Methyl-<span style="font-variant: small-caps">d</span>-Aspartate (NMDA) Receptors
by: Giovanna Casili, et al.
Published: (2022-09-01)

Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model
by: Sarah Adriana Scuderi, et al.
Published: (2022-02-01)

TLR7/8 in the Pathogenesis of Parkinson’s Disease
by: Michela Campolo, et al.
Published: (2020-12-01)

Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
by: Alessia Filippone, et al.
Published: (2023-03-01)

SCFA Treatment Alleviates Pathological Signs of Migraine and Related Intestinal Alterations in a Mouse Model of NTG-Induced Migraine
by: Marika Lanza, et al.
Published: (2021-10-01)

Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion
by: Alessio Ardizzone, et al.
Published: (2022-05-01)

Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling
by: Alessia Filippone, et al.
Published: (2022-12-01)

The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model
by: Giovanna Casili, et al.
Published: (2020-12-01)

The Protective Role of Prolyl Oligopeptidase (POP) Inhibition in Kidney Injury Induced by Renal Ischemia–Reperfusion
by: Giovanna Casili, et al.
Published: (2021-11-01)

Inhibition of Prolyl Oligopeptidase Prevents Consequences of Reperfusion following Intestinal Ischemia
by: Alessia Filippone, et al.
Published: (2021-09-01)

SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration
by: Alessio Ardizzone, et al.
Published: (2022-05-01)

Overview on Common Genes Involved in the Onset of Glioma and on the Role of Migraine as Risk Factor: Predictive Biomarkers or Therapeutic Targets?
by: Giovanna Casili, et al.
Published: (2022-11-01)

The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
by: Laura Cucinotta, et al.
Published: (2022-12-01)

Effect of Melatonin on Psoriatic Phenotype in Human Reconstructed Skin Model
by: Sarah Adriana Scuderi, et al.
Published: (2022-03-01)

TAK1 Inhibitor Enhances the Therapeutic Treatment for Glioblastoma
by: Michela Campolo, et al.
Published: (2020-12-01)

Adenosine Targeting as a New Strategy to Decrease Glioblastoma Aggressiveness
by: Valentina Bova, et al.
Published: (2022-08-01)

Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management
by: Alessia Filippone, et al.
Published: (2022-12-01)

BAY-117082-driven NLRP3 inflammasome inhibition resolves nitro-glycerine (NTG) neuronal damage in in vivo model of migraine
by: Alessia Filippone, et al.
Published: (2022-12-01)

Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model
by: Alessia Filippone, et al.
Published: (2020-07-01)

Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas
by: Marika Lanza, et al.
Published: (2021-04-01)

Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition
by: Rossella Basilotta, et al.
Published: (2023-02-01)

Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration
by: Deborah Mannino, et al.
Published: (2023-06-01)

<i>Ulva pertusa,</i> a Marine Green Alga, Attenuates DNBS-Induced Colitis Damage via NF-κB/Nrf2/SIRT1 Signaling Pathways
by: Alessio Ardizzone, et al.
Published: (2022-07-01)

GSK343, an Inhibitor of Enhancer of Zeste Homolog 2, Reduces Glioblastoma Progression through Inflammatory Process Modulation: Focus on Canonical and Non-Canonical NF-κB/IκBα Pathways
by: Sarah Adriana Scuderi, et al.
Published: (2022-11-01)

The Biological Function of MicroRNAs in Bone Tumors
by: Sarah Adriana Scuderi, et al.
Published: (2022-02-01)

bFGF-like Activity Supported Tissue Regeneration, Modulated Neuroinflammation, and Rebalanced Ca<sup>2+</sup> Homeostasis following Spinal Cord Injury
by: Alessio Ardizzone, et al.
Published: (2023-09-01)

KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
by: Sarah Adriana Scuderi, et al.
Published: (2021-07-01)

Correction: Casili et al. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC). <i>Cancers</i> 2023, <i>15</i>, 2796
by: Giovanna Casili, et al.
Published: (2024-03-01)