New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis

In light chain amyloidosis, a reduction in dFLC to below 40 mg/l is a prerequisite for organ recovery as nearly half of the patients who achieve very good partial haematological responses have improvement in the function of the involved organ. We describe a patient who developed new-onset cardiac am...

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Main Authors: Abiodun Idowu, Lillian Tung, Catherine Chu, Jamario Skeete, Agne Paner, Tochukwu Okwuosa
Format: Article
Language:English
Published: SMC MEDIA SRL 2023-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://ejcrim.com/index.php/EJCRIM/article/view/3768
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author Abiodun Idowu
Lillian Tung
Catherine Chu
Jamario Skeete
Agne Paner
Tochukwu Okwuosa
author_facet Abiodun Idowu
Lillian Tung
Catherine Chu
Jamario Skeete
Agne Paner
Tochukwu Okwuosa
author_sort Abiodun Idowu
collection DOAJ
description In light chain amyloidosis, a reduction in dFLC to below 40 mg/l is a prerequisite for organ recovery as nearly half of the patients who achieve very good partial haematological responses have improvement in the function of the involved organ. We describe a patient who developed new-onset cardiac amyloidosis despite a post-treatment reduction in dFLC to <10 mg/l.
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spelling doaj.art-3f35036b5776433dade7c62df9dfcf212023-02-28T11:41:21ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-02-0110.12890/2023_0037683303New-onset cardiac amyloidosis while in remission from systemic AL amyloidosisAbiodun Idowu0https://orcid.org/0000-0003-4702-9233Lillian Tung1Catherine Chu2Jamario Skeete3Agne Paner4Tochukwu Okwuosa5 Department of Internal Medicine, Einstein Medical Center, Philadelphia, Pennsylvania, USADepartment of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USARush University Medical College, Chicago, Illinois, USADivision of Cardiology, Rush University Medical Center, Chicago, Illinois, USA Division of Hematology/Oncology/Cell Therapy, Rush University Medical Center, Chicago, Illinois, USADivision of Cardiology, Section of Cardio-Oncology, Rush University Medical Center, Chicago, Illinois, USAIn light chain amyloidosis, a reduction in dFLC to below 40 mg/l is a prerequisite for organ recovery as nearly half of the patients who achieve very good partial haematological responses have improvement in the function of the involved organ. We describe a patient who developed new-onset cardiac amyloidosis despite a post-treatment reduction in dFLC to <10 mg/l.https://ejcrim.com/index.php/EJCRIM/article/view/3768light chainplasma cellcardiac amyloidosis
spellingShingle Abiodun Idowu
Lillian Tung
Catherine Chu
Jamario Skeete
Agne Paner
Tochukwu Okwuosa
New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
European Journal of Case Reports in Internal Medicine
light chain
plasma cell
cardiac amyloidosis
title New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
title_full New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
title_fullStr New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
title_full_unstemmed New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
title_short New-onset cardiac amyloidosis while in remission from systemic AL amyloidosis
title_sort new onset cardiac amyloidosis while in remission from systemic al amyloidosis
topic light chain
plasma cell
cardiac amyloidosis
url https://ejcrim.com/index.php/EJCRIM/article/view/3768
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AT lilliantung newonsetcardiacamyloidosiswhileinremissionfromsystemicalamyloidosis
AT catherinechu newonsetcardiacamyloidosiswhileinremissionfromsystemicalamyloidosis
AT jamarioskeete newonsetcardiacamyloidosiswhileinremissionfromsystemicalamyloidosis
AT agnepaner newonsetcardiacamyloidosiswhileinremissionfromsystemicalamyloidosis
AT tochukwuokwuosa newonsetcardiacamyloidosiswhileinremissionfromsystemicalamyloidosis