Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications
Abstract Intricate assembly of multiple molecular chromophores assisted by protein scaffolds is essential in tuning the optical absorption and energy transfer in the light‐harvesting complexes of the photosynthetic systems in nature. However, it remains a challenge to achieve such structural complex...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | Aggregate |
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| Online Access: | https://doi.org/10.1002/agt2.261 |
| _version_ | 1797840332877987840 |
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| author | Cangjie Yang Wei Zhang Xin Pang Fan Xiao Sandeep Kumar Kalva Yipeng Zhang Manojit Pramanik Leilei Tian Gang Liu Mingfeng Wang |
| author_facet | Cangjie Yang Wei Zhang Xin Pang Fan Xiao Sandeep Kumar Kalva Yipeng Zhang Manojit Pramanik Leilei Tian Gang Liu Mingfeng Wang |
| author_sort | Cangjie Yang |
| collection | DOAJ |
| description | Abstract Intricate assembly of multiple molecular chromophores assisted by protein scaffolds is essential in tuning the optical absorption and energy transfer in the light‐harvesting complexes of the photosynthetic systems in nature. However, it remains a challenge to achieve such structural complexity and functionality in synthetic polymer‐chromophore systems. Here, we report a series of polyester‐tethered pyrrolopyrrole cyanine derivatives and their colloidal nanoparticles dispersed in water, which show tunable J‐ or H‐aggregation excitonic coupling and near‐infrared fluorescence by precise control of the polymer chain lengths, composition, and temperature. Moreover, the optimal fluorescence or photothermal effect of the J‐aggregate nanoparticles enables broad applications in fluorescence or photoacoustic bioimaging and phototherapy. |
| first_indexed | 2024-04-09T16:13:14Z |
| format | Article |
| id | doaj.art-3f36e3307f5649588dee2e903a85d1e3 |
| institution | Directory Open Access Journal |
| issn | 2692-4560 |
| language | English |
| last_indexed | 2024-04-09T16:13:14Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Aggregate |
| spelling | doaj.art-3f36e3307f5649588dee2e903a85d1e32023-04-24T08:03:50ZengWileyAggregate2692-45602023-04-0142n/an/a10.1002/agt2.261Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applicationsCangjie Yang0Wei Zhang1Xin Pang2Fan Xiao3Sandeep Kumar Kalva4Yipeng Zhang5Manojit Pramanik6Leilei Tian7Gang Liu8Mingfeng Wang9School of Chemical and Biomedical Engineering Nanyang Technological University Singapore SingaporeSchool of Science and Engineering The Chinese University of Hong Kong Shenzhen ChinaState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen ChinaSchool of Materials Science and Engineering South University of Science and Technology Shenzhen ChinaSchool of Chemical and Biomedical Engineering Nanyang Technological University Singapore SingaporeSchool of Science and Engineering The Chinese University of Hong Kong Shenzhen ChinaSchool of Chemical and Biomedical Engineering Nanyang Technological University Singapore SingaporeSchool of Materials Science and Engineering South University of Science and Technology Shenzhen ChinaState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen ChinaSchool of Chemical and Biomedical Engineering Nanyang Technological University Singapore SingaporeAbstract Intricate assembly of multiple molecular chromophores assisted by protein scaffolds is essential in tuning the optical absorption and energy transfer in the light‐harvesting complexes of the photosynthetic systems in nature. However, it remains a challenge to achieve such structural complexity and functionality in synthetic polymer‐chromophore systems. Here, we report a series of polyester‐tethered pyrrolopyrrole cyanine derivatives and their colloidal nanoparticles dispersed in water, which show tunable J‐ or H‐aggregation excitonic coupling and near‐infrared fluorescence by precise control of the polymer chain lengths, composition, and temperature. Moreover, the optimal fluorescence or photothermal effect of the J‐aggregate nanoparticles enables broad applications in fluorescence or photoacoustic bioimaging and phototherapy.https://doi.org/10.1002/agt2.261bioimagingcolloidsfluorescencepolymersself‐assembly |
| spellingShingle | Cangjie Yang Wei Zhang Xin Pang Fan Xiao Sandeep Kumar Kalva Yipeng Zhang Manojit Pramanik Leilei Tian Gang Liu Mingfeng Wang Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications Aggregate bioimaging colloids fluorescence polymers self‐assembly |
| title | Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications |
| title_full | Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications |
| title_fullStr | Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications |
| title_full_unstemmed | Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications |
| title_short | Polyester‐tethered near‐infrared fluorophores confined in colloidal nanoparticles: Tunable and thermoresponsive aggregation and biomedical applications |
| title_sort | polyester tethered near infrared fluorophores confined in colloidal nanoparticles tunable and thermoresponsive aggregation and biomedical applications |
| topic | bioimaging colloids fluorescence polymers self‐assembly |
| url | https://doi.org/10.1002/agt2.261 |
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