Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin
Fish oil has been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. There has been increasing interest in the relationship of fish oil with skin protection and homeos...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-07-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/16/8/256 |
| _version_ | 1811187378927173632 |
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| author | Tse-Hung Huang Pei-Wen Wang Shih-Chun Yang Wei-Ling Chou Jia-You Fang |
| author_facet | Tse-Hung Huang Pei-Wen Wang Shih-Chun Yang Wei-Ling Chou Jia-You Fang |
| author_sort | Tse-Hung Huang |
| collection | DOAJ |
| description | Fish oil has been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. There has been increasing interest in the relationship of fish oil with skin protection and homeostasis, especially with respect to the omega-3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). The other PUFAs, such as α-linolenic acid (ALA) and linoleic acid (LA), also show a beneficial effect on the skin. The major mechanisms of PUFAs for attenuating cutaneous inflammation are the competition with the inflammatory arachidonic acid and the inhibition of proinflammatory eicosanoid production. On the other hand, PUFAs in fish oil can be the regulators that affect the synthesis and activity of cytokines for promoting wound healing. A systemic review was conducted to demonstrate the association between fish oil supplementation and the benefits to the skin. The following describes the different cosmetic and therapeutic approaches using fatty acids derived from fish oil, especially ALA, LA, DHA, and EPA. This review summarizes the cutaneous application of fish oil and the related fatty acids in the cell-based, animal-based, and clinical models. The research data relating to fish oil treatment of skin disorders suggest a way forward for generating advances in cosmetic and dermatological uses. |
| first_indexed | 2024-04-11T14:02:24Z |
| format | Article |
| id | doaj.art-3f38f617fa9d4737a9efe5438598d976 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T14:02:24Z |
| publishDate | 2018-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-3f38f617fa9d4737a9efe5438598d9762022-12-22T04:20:03ZengMDPI AGMarine Drugs1660-33972018-07-0116825610.3390/md16080256md16080256Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the SkinTse-Hung Huang0Pei-Wen Wang1Shih-Chun Yang2Wei-Ling Chou3Jia-You Fang4Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Keelung, Keelung 20401, TaiwanDepartment of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, TaiwanDepartment of Cosmetic Science, Providence University, Taichung 43301, TaiwanDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Keelung, Keelung 20401, TaiwanPharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan 33302, TaiwanFish oil has been broadly reported as a potential supplement to ameliorate the severity of some skin disorders such as photoaging, skin cancer, allergy, dermatitis, cutaneous wounds, and melanogenesis. There has been increasing interest in the relationship of fish oil with skin protection and homeostasis, especially with respect to the omega-3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). The other PUFAs, such as α-linolenic acid (ALA) and linoleic acid (LA), also show a beneficial effect on the skin. The major mechanisms of PUFAs for attenuating cutaneous inflammation are the competition with the inflammatory arachidonic acid and the inhibition of proinflammatory eicosanoid production. On the other hand, PUFAs in fish oil can be the regulators that affect the synthesis and activity of cytokines for promoting wound healing. A systemic review was conducted to demonstrate the association between fish oil supplementation and the benefits to the skin. The following describes the different cosmetic and therapeutic approaches using fatty acids derived from fish oil, especially ALA, LA, DHA, and EPA. This review summarizes the cutaneous application of fish oil and the related fatty acids in the cell-based, animal-based, and clinical models. The research data relating to fish oil treatment of skin disorders suggest a way forward for generating advances in cosmetic and dermatological uses.http://www.mdpi.com/1660-3397/16/8/256fish oilpolyunsaturated fatty acidomega-3skincosmetologydermatology |
| spellingShingle | Tse-Hung Huang Pei-Wen Wang Shih-Chun Yang Wei-Ling Chou Jia-You Fang Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin Marine Drugs fish oil polyunsaturated fatty acid omega-3 skin cosmetology dermatology |
| title | Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin |
| title_full | Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin |
| title_fullStr | Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin |
| title_full_unstemmed | Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin |
| title_short | Cosmetic and Therapeutic Applications of Fish Oil’s Fatty Acids on the Skin |
| title_sort | cosmetic and therapeutic applications of fish oil s fatty acids on the skin |
| topic | fish oil polyunsaturated fatty acid omega-3 skin cosmetology dermatology |
| url | http://www.mdpi.com/1660-3397/16/8/256 |
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